Ethyl 3-Phenylglycidate

INCI: ETHYL 3-PHENYLGLYCIDATE

CAS Number
121-39-1 [^1_9][^1_10]
Function
Fragrance (perfuming agent), known as Aldehyde C-16 or Strawberry Aldehyde
Safety Rating
GOOD

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status prohibited
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Permitted โ€” FEMA 2454, GRAS status

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
moderate
Sensitization
moderate

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Epoxide structural alert: the glycidate (oxirane) ring is a genotoxicity flag in QSAR models; however, RIFM assessment cleared it. GHS H315 (skin irritation) and H319 (serious eye irritation). Moisture-sensitive; store properly.

โš ๏ธ
Concern Level: High

Regulatory Flags

fragrance-component jecfa_safe

Frequently Asked Questions

Is Ethyl 3-Phenylglycidate safe in cosmetics?

Epoxide structural alert: the glycidate (oxirane) ring is a genotoxicity flag in QSAR models; however, RIFM assessment cleared it. GHS H315 (skin irritation) and H319 (serious eye irritation). Moisture-sensitive; store properly. The EU classifies Ethyl 3-Phenylglycidate as "prohibited". Safety rating: GOOD.

Is Ethyl 3-Phenylglycidate allowed in the EU?

Ethyl 3-Phenylglycidate EU regulatory status: prohibited. This is based on EU Regulation 1223/2009 and its amendments.

What does Ethyl 3-Phenylglycidate do in cosmetics?

Ethyl 3-Phenylglycidate functions as: Fragrance (perfuming agent), known as Aldehyde C-16 or Strawberry Aldehyde. It is classified as a cosmetic ingredient in our database. CAS number: 121-39-1 [^1_9][^1_10].

What is the Margin of Safety for Ethyl 3-Phenylglycidate?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

๐Ÿ“ฑ

Is Ethyl 3-Phenylglycidate in Your Products?

Scan any product label with Piro โ€” our free ingredient scanner. Point your camera at the ingredients list and get instant safety scores for every ingredient.

Try Piro Free โ†’

Analyze Your Full Ingredient List

Paste any INCI list into the Decoder for instant safety analysis, or calculate the Margin of Safety for Ethyl 3-Phenylglycidate in your formulation.