Ethyl 5,5,7-Trimethyl-1-Oxaspirooctane-2-Carboxylate
INCI: ETHYL 5,5,7-TRIMETHYL-1-OXASPIROOCTANE-2-CARBOXYLATE
Regulatory Status
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Safety Data
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Expert Verdict
Epoxide (oxirane) structural alert present in the 1-oxa-spiro ring; genotoxicity QSAR flag identified. Limited public toxicological monograph data available. RIFM full safety assessment or Ames test/in vitro micronucleus testing recommended for CPSR dossier support.
Regulatory Flags
Frequently Asked Questions
Is Ethyl 5,5,7-Trimethyl-1-Oxaspirooctane-2-Carboxylate safe in cosmetics?
Epoxide (oxirane) structural alert present in the 1-oxa-spiro ring; genotoxicity QSAR flag identified. Limited public toxicological monograph data available. RIFM full safety assessment or Ames test/in vitro micronucleus testing recommended for CPSR dossier support. The EU classifies Ethyl 5,5,7-Trimethyl-1-Oxaspirooctane-2-Carboxylate as "prohibited". Safety rating: MODERATE.
Is Ethyl 5,5,7-Trimethyl-1-Oxaspirooctane-2-Carboxylate allowed in the EU?
Ethyl 5,5,7-Trimethyl-1-Oxaspirooctane-2-Carboxylate EU regulatory status: prohibited. This is based on EU Regulation 1223/2009 and its amendments.
What does Ethyl 5,5,7-Trimethyl-1-Oxaspirooctane-2-Carboxylate do in cosmetics?
Ethyl 5,5,7-Trimethyl-1-Oxaspirooctane-2-Carboxylate functions as: Fragrance (perfuming agent), trade name Spiramber. It is classified as a cosmetic ingredient in our database. CAS number: 60599-38-4 (EINECS 262-113-3) [^1_12].
What is the Margin of Safety for Ethyl 5,5,7-Trimethyl-1-Oxaspirooctane-2-Carboxylate?
not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
Compliance Tools
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Related Ingredients
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