Ethyl Arachidonate

INCI: ETHYL ARACHIDONATE

CAS Number
1808-26-0
Function
Emollient, skin conditioning
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Permitted โ€” not restricted under 21 CFR

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
moderate
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Arachidonic acid is a precursor to pro-inflammatory eicosanoids via COX/LOX pathways; ethyl ester is a prodrug releasing arachidonic acid upon skin esterase hydrolysis with potential for localized inflammatory signaling at elevated concentrations, warranting use-level justification in CPSR.

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Concern Level: Moderate

Frequently Asked Questions

Is Ethyl Arachidonate safe in cosmetics?

Arachidonic acid is a precursor to pro-inflammatory eicosanoids via COX/LOX pathways; ethyl ester is a prodrug releasing arachidonic acid upon skin esterase hydrolysis with potential for localized inflammatory signaling at elevated concentrations, warranting use-level justification in CPSR. The EU classifies Ethyl Arachidonate as "permitted". Safety rating: MODERATE.

Is Ethyl Arachidonate allowed in the EU?

Ethyl Arachidonate EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Ethyl Arachidonate do in cosmetics?

Ethyl Arachidonate functions as: Emollient, skin conditioning. It is classified as a cosmetic ingredient in our database. CAS number: 1808-26-0.

What is the Margin of Safety for Ethyl Arachidonate?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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