Regulatory Status
For full compliance data across 55 jurisdictions, use the Substance Compliance tool.
Safety Data
Calculate MoS for your specific formulation with the MoS Calculator.
Toxicological Studies
1 study endpoint found for Ethyl Isobutyrate. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.
| Endpoint | Value | Route | Species | Study Type | Source |
|---|---|---|---|---|---|
| NOAEL | 29.2 mg/kg bw/day | oral | rat | Subchronic | COSMOS_DB |
Expert Verdict
Not phototoxic; not PBT; no environmental risk identified; Cramer Class I
Regulatory Flags
Frequently Asked Questions
Is Ethyl Isobutyrate safe in cosmetics?
Not phototoxic; not PBT; no environmental risk identified; Cramer Class I The EU classifies Ethyl Isobutyrate as "permitted". Safety rating: GOOD. 1 toxicological study endpoint(s) are available in our database.
Is Ethyl Isobutyrate allowed in the EU?
Ethyl Isobutyrate EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Ethyl Isobutyrate do in cosmetics?
Ethyl Isobutyrate functions as: Fragrance. It is classified as a cosmetic ingredient in our database. CAS number: 97-62-1.
What is the Margin of Safety for Ethyl Isobutyrate?
adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
What is the NOAEL for Ethyl Isobutyrate?
The NOAEL (No Observed Adverse Effect Level) for Ethyl Isobutyrate is 29.2 mg/kg bw/day based on a Subchronic study via oral route in rat. Source: COSMOS_DB.
Compliance Tools
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Related Ingredients
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