Good Cosmetic Ingredient NOAEL Data

Ethyl Lactate

INCI: ETHYL LACTATE

CAS Number
97-64-3
Function
Solvent, fragrance ingredient, skin-conditioning agent
Safety Rating
GOOD

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Permitted โ€” no specific CFR restriction; FEMA GRAS

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
moderate
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Toxicological Studies

1 study endpoint found for Ethyl Lactate. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.

Endpoint Value Route Species Study Type Source
NOAEL ca.600 mg/kg bw/day oral rat oral REACH

Expert Verdict

Skin and eye irritation possible at high concentrations; not genotoxic or phototoxic/photoallergenic based on UV spectra.

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Concern Level: Low

Regulatory Flags

potential-allergen fragrance-component epa_safer_alternative ifra_fragrance fda_food_additive

Frequently Asked Questions

Is Ethyl Lactate safe in cosmetics?

Skin and eye irritation possible at high concentrations; not genotoxic or phototoxic/photoallergenic based on UV spectra. The EU classifies Ethyl Lactate as "permitted". Safety rating: GOOD. 1 toxicological study endpoint(s) are available in our database.

Is Ethyl Lactate allowed in the EU?

Ethyl Lactate EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Ethyl Lactate do in cosmetics?

Ethyl Lactate functions as: Solvent, fragrance ingredient, skin-conditioning agent. It is classified as a cosmetic ingredient in our database. CAS number: 97-64-3.

What is the Margin of Safety for Ethyl Lactate?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

What is the NOAEL for Ethyl Lactate?

The NOAEL (No Observed Adverse Effect Level) for Ethyl Lactate is ca.600 mg/kg bw/day based on a oral study via oral route in rat. Source: REACH.

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