Is Ethyl Perfluorobutyl Ether safe in cosmetics?
Ethyl Perfluorobutyl Ether has a safety rating of "MODERATE" in our database. EU status: permitted. US status: permitted.
Moderate
Cosmetic Ingredient
Ethyl Perfluorobutyl Ether
Also known as: Ethyl nonafluorobutyl ether, 1-(Ethoxy)nonafluorobutane, Butane, 1-ethoxy-1,1,2,2,3,3,4,4,4-nonafluoro-, (Perfluorobutoxy)ethane, Nonafluorobutyl ethyl ether (+15 more)
INCI: ETHYL PERFLUOROBUTYL ETHER
Ethyl Perfluorobutyl Ether (CAS 163702-05-4) is a cosmetic cosmetic ingredient functioning as Solvent. EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety data.
View industrial chemical safety profile for CAS 163702-05-4 →
Auto-generated CPSR Part A draft with source citations
Cross-Vertical Regulatory Divergence
Ethyl Perfluorobutyl Ether is classified GHS Danger (H315, H413, H225, H319, H335) in the chemicals database but is allowed in EU cosmetics.
Source: Cosmetics: ingredients.eu_status; Chemicals: ghs_classifications.signal_word/hazard_statement_code
Function
Solvent
Safety Rating
MODERATE
Chemistry & Identifiers
IUPAC Name
1-ethoxy-1,1,2,2,3,3,4,4,4-nonafluorobutane
InChIKey
DFUYAWQUODQGFF-UHFFFAOYSA-N
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
Currently permitted — EPA PFAS regulations evolving; no specific CFR cosmetic prohibition yet
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Ethyl Perfluorobutyl Ether.
Calculate MoS for your specific formulation with the MoS Calculator.
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Solvent
Expert Verdict
Expert safety assessment and concern-level summary for Ethyl Perfluorobutyl Ether.
Known Synonyms
Ethyl nonafluorobutyl ether
1-(Ethoxy)nonafluorobutane
Butane, 1-ethoxy-1,1,2,2,3,3,4,4,4-nonafluoro-
(Perfluorobutoxy)ethane
Nonafluorobutyl ethyl ether
EEC No.: 425-340-0
ELINCS No.: 425-340-0
EC No.: 425-340-0
EC No.: 922-358-5
UNII-520BW6FQ5U
HFE-569sf2 (HFE-7200) Chemical blend
C4F9OC2H5
CF 76
Cosmetic Fluid CF 76
HFE 569mccc
HFE 569sf2
HFE 7200
Novec 7200
Novec HFE 7200
HFE-7200 3M Speciality Liquid
Chemical Function
Solvent
Regulatory Lists
Europe
Frequently Asked Questions
Is Ethyl Perfluorobutyl Ether allowed in the EU?
Ethyl Perfluorobutyl Ether EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Ethyl Perfluorobutyl Ether do in cosmetics?
Ethyl Perfluorobutyl Ether functions as: Solvent. It is classified as a cosmetic ingredient in our database. CAS number: 163702-05-4.
Is Ethyl Perfluorobutyl Ether used outside cosmetics?
Ethyl Perfluorobutyl Ether also appears in industrial chemical safety data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Does Ethyl Perfluorobutyl Ether have different safety status in cosmetics vs industrial chemicals?
Ethyl Perfluorobutyl Ether is classified GHS Danger (H315, H413, H225, H319, H335) in the chemicals database but is allowed in EU cosmetics.
Compliance Tools
Check Ethyl Perfluorobutyl Ether compliance across multiple jurisdictions:
Ingredient Decoder
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82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
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MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
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Chemical family
Solvent
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