Euphorbia Maculata Callus Extract

INCI: EUPHORBIA MACULATA CALLUS EXTRACT

CAS Number
Not assigned
Function
Skin conditioning
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Permitted by omission โ€” no CIR review

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
moderate
Sensitization
moderate

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Callus extract includes intracellular contents and shows antioxidant, anti-inflammatory, and antimicrobial activities. Gamma irradiation studies demonstrate modifiable metabolite profiles. Higher risk than conditioned media due to inclusion of intracellular metabolites. Must screen for diterpene ester content; UPLC-QTOF/MS characterization recommended per batch.

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Concern Level: Moderate

Regulatory Flags

plant-extract

Frequently Asked Questions

Is Euphorbia Maculata Callus Extract safe in cosmetics?

Callus extract includes intracellular contents and shows antioxidant, anti-inflammatory, and antimicrobial activities. Gamma irradiation studies demonstrate modifiable metabolite profiles. Higher risk than conditioned media due to inclusion of intracellular metabolites. Must screen for diterpene ester content; UPLC-QTOF/MS characterization recommended per batch. The EU classifies Euphorbia Maculata Callus Extract as "permitted". Safety rating: MODERATE.

Is Euphorbia Maculata Callus Extract allowed in the EU?

Euphorbia Maculata Callus Extract EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Euphorbia Maculata Callus Extract do in cosmetics?

Euphorbia Maculata Callus Extract functions as: Skin conditioning. It is classified as a cosmetic ingredient in our database. CAS number: Not assigned.

What is the Margin of Safety for Euphorbia Maculata Callus Extract?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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