Is Ferrous Gluconate safe in cosmetics?
Ferrous Gluconate has a safety rating of "GOOD" in our database. EU status: permitted. US status: permitted.
Good
Cosmetic Ingredient
Ferrous Gluconate
Also known as: Biofergate, Cerevon, EINECS 206-076-3, Feravol, Fergon preparations (+15 more)
INCI: FERROUS GLUCONATE
Ferrous Gluconate (CAS 299-29-6) is a cosmetic cosmetic ingredient functioning as Skin Conditioning. EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety and pharmaceutical data.
View industrial chemical safety profile for CAS 299-29-6 →
Auto-generated CPSR Part A draft with source citations
Function
Skin Conditioning
Safety Rating
GOOD
Chemistry & Identifiers
IUPAC Name
iron(2+);bis((2R,3S,4R,5R)-2,3,4,5,6-pentahydroxyhexanoate)
InChIKey
VRIVJOXICYMTAG-IYEMJOQQSA-L
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
Permitted; FDA-approved color additive for ripe olives (21 CFR 73.170); pharmaceutical-grade iron supplement
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Ferrous Gluconate.
Calculate MoS for your specific formulation with the MoS Calculator.
ECHA REACH Registration
European Chemicals Agency REACH dossier and Substances of Very High Concern listing.
Registration Type
Full
Tonnage Band
100 - 1,000 tonnes
Substance Type
SUBSTANCE
SVHC Candidate
No
PubChem Annotations
Safety and regulatory annotations from PubChem (NCBI) aggregated sources.
Safety (1)
Skin Eye Respiratory Irritation
If inhaled, iron is a local irritant to the lung and gastrointestinal tract. /Iron compounds/
Source: Hazardous Substances Data Bank (HSDB)
Regulatory (1)
EU Food Improvement
Food additives
Source: EU Food Improvement Agents
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Dye
Softener and conditioner
Expert Verdict
Expert safety assessment and concern-level summary for Ferrous Gluconate.
Known Synonyms
Biofergate
Cerevon
EINECS 206-076-3
Feravol
Fergon preparations
Ferlucon
Ferro-agepha
Ferroglyconicum
Ferronicum
Ferrose
Ferrum polon
Glucoferron
Gluco-ferrum
Glucomax
Gluconic acid iron salt
Gluconic acid, iron(2+) salt (2:1), D-
Gluferate
Iron gluconate
Iron-II gluconate
Nionate
Chemical Function
Softener and conditioner
Dye
Regulatory Lists
active_ingredient; Australia
general_foods
Europe; supplements
Europe; food_additive; supplements
Canada; pharmaceutical
Australian Status
AICIS status: listed
Cross-Vertical Safety Context
Same-CAS public records found in pharmaceutical data.
SOURCE
ChEMBL / DrugCentral / FAERS
DB_PHARMA CAS match
Pharmaceutical Data
Same-CAS rows from the pharmaceutical spoke database.
Compound
ferrous gluconate
ChEMBL ID
CHEMBL1201494
Adverse Event Associations
164
Frequently Asked Questions
Is Ferrous Gluconate allowed in the EU?
Ferrous Gluconate EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Ferrous Gluconate do in cosmetics?
Ferrous Gluconate functions as: Skin Conditioning. It is classified as a cosmetic ingredient in our database. CAS number: 299-29-6.
Is Ferrous Gluconate used outside cosmetics?
Ferrous Gluconate also appears in industrial chemical safety and pharmaceutical data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Compliance Tools
Check Ferrous Gluconate compliance across multiple jurisdictions:
Ingredient Decoder
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82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
Check compliance across multiple jurisdictions
MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
Compare limits across jurisdictions
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(AGARICUS BLAZEI FERMENT + GANODERMA LUCIDUM FERMENT + GANODERMA MULTIPILEUM FERMENT) EXTRACT
Good
Similar safety
Anti-sebum, Antioxidant, Skin Protecting
(ANGELICA ACUTILOBA/PAEONIA LACTIFLORA/REHMANNIA GLUTINOSA) ROOT/CNIDIUM OFFICINALE RHIZOME EXTRACT
Good
Similar safety
Skin Conditioning, Skin Conditioning ...
(ANGELICA ACUTILOBA/PAEONIA LACTIFLORA/REHMANNIA GLUTINOSA/SCUTELLARIA BAICALENSIS) ROOT/(CNIDIUM OFFICINALE/COPTIS CHINENSIS) RHIZOME/GARDENIA JASMINOIDES FRUIT/PHELLODENDRON CHINENSE BARK EXTRACT
Good
Similar safety
(ANGELICA GIGAS/GLYCYRRHIZA URALENSIS/REHMANNIA GLUTINOSA ROOT)/ANGELICA GIGAS STEM/CARTHAMUS TINCTORIUS FLOWER/(CARTHAMUS TINCTORIUS/PRUNUS PERSICA SEED)PORIA COCOS WATER
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Humectant, Skin Conditioning, Skin Pr...
(ANGELICA KEISKEI/CHRYSANTHEMUM ZAWADSKII) LEAF/STEM/CINNAMOMUM CASSIA BARK/TRICHOSANTES KIRILOWII FRUIT/ULMUS DAVIDIANA BARK/ROOT/(PAEONIA JAPONICA/BUPLEURUM FALCATUM/POLYGALA TENUIFOLIA ROOT)/VISCUS ALBUM STEM EXTRACT
Good
Similar safety
Anti-seborrheic, Anti-sebum, Antioxid...
(APPLE/CITRUS JUNOS/LENTIL/PEAR/PUMPKIN/STRAWBERRY/TOMATO FRUIT)/CORN KERNEL/(ARCTIUM LAPPA/BRASSICA OLERACEA ACEPHALA/CABBAGE/CAMELLIA SINENSIS/MORINGA OLEIFERA/RADISH/SPINACH LEAF)/(SORGHUM BICOLOR LEAF/STEM)/OAT MEAL/POTATO PULP/(CARROT/NELUMBO NUCIFERA/RADISH/WILD YAM ROOT)/(AMARANTHUS HYPOCHONDRIACUS/CASHEW/CICER ARIETINUM/COIX LACRYMA-JOBI MA-YUEN /MACADAMIA TERNIFOLIA/PHASEOLUS ANGULARIS/PISTACIA VERA/RHYNCHOSIA NULUBILIS/RICE/SESAME/SETARIA ITALICA/SOYBEAN/SWEET ALMOND/WHEAT SEED)/HORDEUM VULGARE SPROUT/CYPERUS ESCULENTUS TUBER/ARTEMISIA PRINCEPS/BROCCOLI/CHENOPODIUM QUINOA/ENTEROMORPHA COMPRESSA/HORDEUM VULGARE/IPOMOEA BATATAS/LAMINARIA JAPONICA/LENTINUS EDODES/PLEUROTUS OSTREATUS/PORPHYRA TENERA/UNDARIA PINNATIFIDA EXTRACT
Good
Similar safety
Antioxidant
Calcium Gluconate
Excellent
Chemical family
Chelating agent, Skin conditioning agent
Potassium Gluconate
Excellent
Chemical family
Chelating agent, skin protecting
FERULA GALBANIFLUA GUM EXTRACT
Good
Browse nearby
Antimicrobial, Perfuming, Tonic
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