Moderate Cosmetic Ingredient NOAEL Data

Ferrous Lactate

INCI: FERROUS LACTATE

CAS Number
5905-52-2
Function
Skin conditioning
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Permitted โ€” FDA GRAS for food use under 21 CFR ยง184.1311; no specific cosmetic prohibition

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Toxicological Studies

3 study endpoints found for Ferrous Lactate. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.

Endpoint Value Route Species Study Type Source
NOAEL 5000 mg/kg bw/day oral rat Short Term Toxicity COSMOS_DB
NOAEL 313 mg/kg bw/day oral rat Subchronic COSMOS_DB
NOAEL 625 mg/kg bw/day oral rat Short Term Toxicity COSMOS_DB

Expert Verdict

Iron(II) ions may catalyze Fenton reactions generating free radicals on skin; irritation potential at elevated concentrations and pro-oxidant risk in formulations with oxidation-sensitive actives.

โš ๏ธ
Concern Level: Moderate

Regulatory Flags

fda_food_additive

Frequently Asked Questions

Is Ferrous Lactate safe in cosmetics?

Iron(II) ions may catalyze Fenton reactions generating free radicals on skin; irritation potential at elevated concentrations and pro-oxidant risk in formulations with oxidation-sensitive actives. The EU classifies Ferrous Lactate as "permitted". Safety rating: MODERATE. 3 toxicological study endpoint(s) are available in our database.

Is Ferrous Lactate allowed in the EU?

Ferrous Lactate EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Ferrous Lactate do in cosmetics?

Ferrous Lactate functions as: Skin conditioning. It is classified as a cosmetic ingredient in our database. CAS number: 5905-52-2.

What is the Margin of Safety for Ferrous Lactate?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

What is the NOAEL for Ferrous Lactate?

The NOAEL (No Observed Adverse Effect Level) for Ferrous Lactate is 5000 mg/kg bw/day based on a Short Term Toxicity study via oral route in rat. A total of 3 study endpoints are available. Source: COSMOS_DB.

๐Ÿ“ฑ

Is Ferrous Lactate in Your Products?

Scan any product label with Piro โ€” our free ingredient scanner. Point your camera at the ingredients list and get instant safety scores for every ingredient.

Try Piro Free โ†’

Analyze Your Full Ingredient List

Paste any INCI list into the Decoder for instant safety analysis, or calculate the Margin of Safety for Ferrous Lactate in your formulation.