Is Fluorescent Brightener 236 safe in cosmetics?
Fluorescent Brightener 236 has a safety rating of "MODERATE" in our database. EU status: permitted. US status: permitted. 3 toxicological study endpoint(s) are available in our database.
Fluorescent Brightener 236
INCI: FLUORESCENT BRIGHTENER 236
Fluorescent Brightener 236 (CAS 3426-43-5) is a cosmetic cosmetic ingredient functioning as UV absorber. Reported NOAEL =750 mg/kg bw/day in Dog (ToxValDB_ECHA_IUCLID); EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety data.
View industrial chemical safety profile for CAS 3426-43-5 →
Auto-generated CPSR Part A draft with source citations
Function
UV absorber
Safety Rating
MODERATE
Chemistry & Identifiers
IUPAC Name
disodium;5-[(4-anilino-6-methoxy-1,3,5-triazin-2-yl)amino]-2-[(E)-2-[4-[(4-anilino-6-methoxy-1,3,5-triazin-2-yl)amino]-2-sulfonatophenyl]ethenyl]benzenesulfonate
InChIKey
BDYOOAPDMVGPIQ-QDBORUFSSA-L
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
Permitted — no specific restriction
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Fluorescent Brightener 236.
Calculate MoS for your specific formulation with the MoS Calculator.
Toxicological Studies
3 study endpoints found for Fluorescent Brightener 236. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.
| Endpoint | Value | Route | Species | Study Type | Source |
|---|---|---|---|---|---|
| NOAEL | =750 mg/kg bw/day | oral | Dog | subchronic | ToxValDB_ECHA_IUCLID |
| NOAEL | =937.5 mg/kg bw/day | oral | Mouse | reproduction developmental | ToxValDB_ECHA_IUCLID |
| NOAEL | =1000 mg/kg bw/day | oral | Rat | reproduction developmental | ToxValDB_ECHA_IUCLID |
ECHA REACH Registration
European Chemicals Agency REACH dossier and Substances of Very High Concern listing.
Registration Type
Full
Tonnage Band
10 - 100 tonnes
Substance Type
SUBSTANCE
SVHC Candidate
No
Expert Verdict
Expert safety assessment and concern-level summary for Fluorescent Brightener 236.
NOAEL Studies Summary
View details ->Public NOAEL study rows linked to Fluorescent Brightener 236 by CAS number or substance name.
Studies
3
Lowest NOAEL
750 mg/kg bw/day
Highest NOAEL
1000 mg/kg bw/day
ToxValDB_ECHA_IUCLID
Australian Status
AICIS status: listed
Frequently Asked Questions
Is Fluorescent Brightener 236 allowed in the EU?
Fluorescent Brightener 236 EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Fluorescent Brightener 236 do in cosmetics?
Fluorescent Brightener 236 functions as: UV absorber. It is classified as a cosmetic ingredient in our database. CAS number: 3426-43-5.
What is the NOAEL for Fluorescent Brightener 236?
The NOAEL (No Observed Adverse Effect Level) for Fluorescent Brightener 236 is =750 mg/kg bw/day based on a subchronic study via oral route in Dog. A total of 3 study endpoints are available. Source: ToxValDB_ECHA_IUCLID.
Is Fluorescent Brightener 236 used outside cosmetics?
Fluorescent Brightener 236 also appears in industrial chemical safety data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Compliance Tools
Check Fluorescent Brightener 236 compliance across multiple jurisdictions:
Ingredient Decoder
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Substance Compliance
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MoS Calculator
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Heavy Metal Limits
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