Frangula Alnus Bark

INCI: FRANGULA ALNUS BARK

CAS Number
84625-48-9
Function
Skin Conditioning, Skin Protecting
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Permitted โ€” no specific restriction under 21 CFR; recognized as botanical ingredient

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
moderate
Sensitization
moderate

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Contains anthraquinones (frangulin A/B, emodin, chrysophanol). Emodin has shown genotoxic signals in some in-vitro assays. China restricts leave-on use to โ‰ค0.00363% and rinse-off to โ‰ค0.2%. A safety assessor will likely require emodin quantification and a justified use level. Recommend supplier-provided anthraquinone specification and in-vitro genotoxicity data.

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Concern Level: High

Frequently Asked Questions

Is Frangula Alnus Bark safe in cosmetics?

Contains anthraquinones (frangulin A/B, emodin, chrysophanol). Emodin has shown genotoxic signals in some in-vitro assays. China restricts leave-on use to โ‰ค0.00363% and rinse-off to โ‰ค0.2%. A safety assessor will likely require emodin quantification and a justified use level. Recommend supplier-provided anthraquinone specification and in-vitro genotoxicity data. The EU classifies Frangula Alnus Bark as "permitted". Safety rating: MODERATE.

Is Frangula Alnus Bark allowed in the EU?

Frangula Alnus Bark EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Frangula Alnus Bark do in cosmetics?

Frangula Alnus Bark functions as: Skin Conditioning, Skin Protecting. It is classified as a cosmetic ingredient in our database. CAS number: 84625-48-9.

What is the Margin of Safety for Frangula Alnus Bark?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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