gamma-Docosalactone

INCI: GAMMA-DOCOSALACTONE

CAS Number
21351-39-3 (verify against CosIng)
Function
Hair conditioning, skin conditioning
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Permitted โ€” no specific 21 CFR restriction; not a fragrance ingredient

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
negligible
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

No publicly available RIFM or CIR safety assessment found. Relatively new ingredient primarily used in Japanese and Asian haircare; long-chain lactone structure is inherently low-risk, but formal safety dossier is absent and may be required for comprehensive safety review.

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Concern Level: Moderate

Regulatory Flags

potential-allergen

Frequently Asked Questions

Is gamma-Docosalactone safe in cosmetics?

No publicly available RIFM or CIR safety assessment found. Relatively new ingredient primarily used in Japanese and Asian haircare; long-chain lactone structure is inherently low-risk, but formal safety dossier is absent and may be required for comprehensive safety review. The EU classifies gamma-Docosalactone as "permitted". Safety rating: MODERATE.

Is gamma-Docosalactone allowed in the EU?

gamma-Docosalactone EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does gamma-Docosalactone do in cosmetics?

gamma-Docosalactone functions as: Hair conditioning, skin conditioning. It is classified as a cosmetic ingredient in our database. CAS number: 21351-39-3 (verify against CosIng).

What is the Margin of Safety for gamma-Docosalactone?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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