gamma-Methylenedihydrocinnamyl acetate

INCI: GAMMA-METHYLENEDIHYDROCINNAMYL ACETATE

CAS Number
Requires verification (probable structure: 2-methylene-4-phenylbutyl acetate or related)
Function
Fragrance
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status prohibited
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Presumed permitted as fragrance under 21 CFR

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
moderate
Sensitization
moderate

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

DATA GAP: The methylene group warrants scrutiny as a potential electrophilic center for skin sensitization. Dihydrocinnamyl (saturated) esters are generally safer than their unsaturated cinnamyl analogs. Recommend supplier tox dossier, in vitro sensitization battery, and confirmation of CAS/structural identity before CPSR finalization.

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Concern Level: Moderate

Regulatory Flags

potential-allergen fragrance-component

Frequently Asked Questions

Is gamma-Methylenedihydrocinnamyl acetate safe in cosmetics?

DATA GAP: The methylene group warrants scrutiny as a potential electrophilic center for skin sensitization. Dihydrocinnamyl (saturated) esters are generally safer than their unsaturated cinnamyl analogs. Recommend supplier tox dossier, in vitro sensitization battery, and confirmation of CAS/structural identity before CPSR finalization. The EU classifies gamma-Methylenedihydrocinnamyl acetate as "prohibited". Safety rating: MODERATE.

Is gamma-Methylenedihydrocinnamyl acetate allowed in the EU?

gamma-Methylenedihydrocinnamyl acetate EU regulatory status: prohibited. This is based on EU Regulation 1223/2009 and its amendments.

What does gamma-Methylenedihydrocinnamyl acetate do in cosmetics?

gamma-Methylenedihydrocinnamyl acetate functions as: Fragrance. It is classified as a cosmetic ingredient in our database. CAS number: Requires verification (probable structure: 2-methylene-4-phenylbutyl acetate or related).

What is the Margin of Safety for gamma-Methylenedihydrocinnamyl acetate?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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