Garcinia Mangostana Bark Extract

INCI: GARCINIA MANGOSTANA BARK EXTRACT

CAS Number
90045-25-3
Function
Skin conditioning
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Permitted โ€” not restricted under 21 CFR 250/700

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
moderate
Sensitization
moderate

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Bark extracts may contain higher xanthone concentrations (ฮฑ-mangostin ~30% in ethanol extracts); cytotoxic activity documented at high concentrations; solvent residue specifications needed; less commercial history than fruit/pericarp derivatives.

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Concern Level: Moderate

Regulatory Flags

plant-extract

Frequently Asked Questions

Is Garcinia Mangostana Bark Extract safe in cosmetics?

Bark extracts may contain higher xanthone concentrations (ฮฑ-mangostin ~30% in ethanol extracts); cytotoxic activity documented at high concentrations; solvent residue specifications needed; less commercial history than fruit/pericarp derivatives. The EU classifies Garcinia Mangostana Bark Extract as "permitted". Safety rating: MODERATE.

Is Garcinia Mangostana Bark Extract allowed in the EU?

Garcinia Mangostana Bark Extract EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Garcinia Mangostana Bark Extract do in cosmetics?

Garcinia Mangostana Bark Extract functions as: Skin conditioning. It is classified as a cosmetic ingredient in our database. CAS number: 90045-25-3.

What is the Margin of Safety for Garcinia Mangostana Bark Extract?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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