Gastrodin

INCI: GASTRODIN

CAS Number
62499-27-8
Function
Skin conditioning; skin lightening active (tyrosinase inhibitor)
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Permitted โ€” no specific CFR restriction; FDA UNII: 5YS9U2W3RQ

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
low
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Gastrodin is a skin-conditioning tyrosinase inhibitor with GHS07 hazard classification (H302); purity specification critical (โ‰ฅ98% pharmaceutical grade); no published cosmetic-specific safety assessment; risk profile varies depending on isolated compound versus extract matrix formulation.

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Concern Level: Moderate

Frequently Asked Questions

Is Gastrodin safe in cosmetics?

Gastrodin is a skin-conditioning tyrosinase inhibitor with GHS07 hazard classification (H302); purity specification critical (โ‰ฅ98% pharmaceutical grade); no published cosmetic-specific safety assessment; risk profile varies depending on isolated compound versus extract matrix formulation. The EU classifies Gastrodin as "permitted". Safety rating: MODERATE.

Is Gastrodin allowed in the EU?

Gastrodin EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Gastrodin do in cosmetics?

Gastrodin functions as: Skin conditioning; skin lightening active (tyrosinase inhibitor). It is classified as a cosmetic ingredient in our database. CAS number: 62499-27-8.

What is the Margin of Safety for Gastrodin?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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