Gentiana Scabra Root Extract

INCI: GENTIANA SCABRA ROOT EXTRACT

CAS Number
95193-52-5 / 22255-40-9; EINECS 305-864-5
Function
Skin conditioning — barrier strengthening, anti-inflammatory, anti-aging
Safety Rating
MODERATE

Regulatory Status

🇪🇺 EU Status permitted
🇺🇸 US Status permitted
US Notes Permitted — not restricted under 21 CFR

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Recommended use level 2–5% by suppliers; most-commercialized of the non-lutea Gentiana species, but lacks formal dermal toxicology dossier and complete biodegradability assessment of certain components.

⚠️
Concern Level: Moderate

Regulatory Flags

plant-extract

Frequently Asked Questions

Is Gentiana Scabra Root Extract safe in cosmetics?

Recommended use level 2–5% by suppliers; most-commercialized of the non-lutea Gentiana species, but lacks formal dermal toxicology dossier and complete biodegradability assessment of certain components. The EU classifies Gentiana Scabra Root Extract as "permitted". Safety rating: MODERATE.

Is Gentiana Scabra Root Extract allowed in the EU?

Gentiana Scabra Root Extract EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Gentiana Scabra Root Extract do in cosmetics?

Gentiana Scabra Root Extract functions as: Skin conditioning — barrier strengthening, anti-inflammatory, anti-aging. It is classified as a cosmetic ingredient in our database. CAS number: 95193-52-5 / 22255-40-9; EINECS 305-864-5.

What is the Margin of Safety for Gentiana Scabra Root Extract?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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