Glutamylamidoethyl Indole

INCI: GLUTAMYLAMIDOETHYL INDOLE

CAS Number
478273-36-8
Function
Skin protecting
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Permitted โ€” not restricted under 21 CFR

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Structurally related to melatonin-pathway molecules; likely supplied by same manufacturer as Chronocyclin (Biosil). Request supplier tox dossier for CPSR. PubMed search yields no independent safety studies.

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Concern Level: Moderate

Frequently Asked Questions

Is Glutamylamidoethyl Indole safe in cosmetics?

Structurally related to melatonin-pathway molecules; likely supplied by same manufacturer as Chronocyclin (Biosil). Request supplier tox dossier for CPSR. PubMed search yields no independent safety studies. The EU classifies Glutamylamidoethyl Indole as "permitted". Safety rating: MODERATE.

Is Glutamylamidoethyl Indole allowed in the EU?

Glutamylamidoethyl Indole EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Glutamylamidoethyl Indole do in cosmetics?

Glutamylamidoethyl Indole functions as: Skin protecting. It is classified as a cosmetic ingredient in our database. CAS number: 478273-36-8.

What is the Margin of Safety for Glutamylamidoethyl Indole?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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