Glycol Dipivalate

INCI: GLYCOL DIPIVALATE

CAS Number
Not confirmed in public databases
Function
Skin conditioning
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Permitted โ€” no CFR restriction; no CIR review

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
moderate
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Pivalic acid moiety may interfere with carnitine conjugation at systemic exposure; relevant only if significant dermal absorption occurs. Virtually no published cosmetic safety data โ€” would require full tox package for CPSR.

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Concern Level: Moderate

Frequently Asked Questions

Is Glycol Dipivalate safe in cosmetics?

Pivalic acid moiety may interfere with carnitine conjugation at systemic exposure; relevant only if significant dermal absorption occurs. Virtually no published cosmetic safety data โ€” would require full tox package for CPSR. The EU classifies Glycol Dipivalate as "permitted". Safety rating: MODERATE.

Is Glycol Dipivalate allowed in the EU?

Glycol Dipivalate EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Glycol Dipivalate do in cosmetics?

Glycol Dipivalate functions as: Skin conditioning. It is classified as a cosmetic ingredient in our database. CAS number: Not confirmed in public databases.

What is the Margin of Safety for Glycol Dipivalate?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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