Glycol Salicylate

INCI: GLYCOL SALICYLATE

CAS Number
| 2
Function
Skin conditioning, penetration enhancer, analgesic (topical)
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status prohibited
EU Max Conc. 0.5%
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Permitted โ€” no specific CFR restriction for cosmetic use; salicylic acid is OTC active at 0.5โ€“2% (21 CFR 333) for acne

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
moderate

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Glycol salicylate is prohibited in the EU but permitted in the US for cosmetic use without specific restrictions; salicylate derivatives have moderate safety concern and moderate sensitization potential.

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Concern Level: Moderate

Frequently Asked Questions

Is Glycol Salicylate safe in cosmetics?

Glycol salicylate is prohibited in the EU but permitted in the US for cosmetic use without specific restrictions; salicylate derivatives have moderate safety concern and moderate sensitization potential. The EU classifies Glycol Salicylate as "prohibited". Safety rating: MODERATE.

Is Glycol Salicylate allowed in the EU?

Glycol Salicylate EU regulatory status: prohibited. Maximum allowed concentration: 0.5%. This is based on EU Regulation 1223/2009 and its amendments.

What does Glycol Salicylate do in cosmetics?

Glycol Salicylate functions as: Skin conditioning, penetration enhancer, analgesic (topical). It is classified as a cosmetic ingredient in our database. CAS number: | 2.

What is the Margin of Safety for Glycol Salicylate?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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