Glycyrrhiza Glabra Leaf Extract

INCI: GLYCYRRHIZA GLABRA LEAF EXTRACT

CAS Number
84775-66-6
Function
Skin conditioning — anti-inflammatory, soothing, antioxidant
Safety Rating
EXCELLENT

Regulatory Status

🇪🇺 EU Status permitted
🇺🇸 US Status permitted
US Notes Permitted — no CFR restriction; CIR concluded safe in present practices of use and concentration

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
low
Sensitization
none

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

May contain glabridin, which has depigmentation properties; CIR Panel noted it would be present at very low concentration in cosmetic formulations. Variation in constituents with different extraction solvents did not present different toxicity issues.

⚠️
Concern Level: Low

Regulatory Flags

plant-extract

Frequently Asked Questions

Is Glycyrrhiza Glabra Leaf Extract safe in cosmetics?

May contain glabridin, which has depigmentation properties; CIR Panel noted it would be present at very low concentration in cosmetic formulations. Variation in constituents with different extraction solvents did not present different toxicity issues. The EU classifies Glycyrrhiza Glabra Leaf Extract as "permitted". Safety rating: EXCELLENT.

Is Glycyrrhiza Glabra Leaf Extract allowed in the EU?

Glycyrrhiza Glabra Leaf Extract EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Glycyrrhiza Glabra Leaf Extract do in cosmetics?

Glycyrrhiza Glabra Leaf Extract functions as: Skin conditioning — anti-inflammatory, soothing, antioxidant. It is classified as a cosmetic ingredient in our database. CAS number: 84775-66-6.

What is the Margin of Safety for Glycyrrhiza Glabra Leaf Extract?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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