Regulatory Status
For full compliance data across 55 jurisdictions, use the Substance Compliance tool.
Safety Data
Calculate MoS for your specific formulation with the MoS Calculator.
Toxicological Studies
1 study endpoint found for Glycyrrhiza Glabra Root. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.
| Endpoint | Value | Route | Species | Study Type | Source |
|---|---|---|---|---|---|
| NOAEL | 1500 mg/kg bw/day | oral | rat | Short Term Toxicity | COSMOS_DB |
Expert Verdict
Same glycyrrhizic acid concerns as other licorice derivatives; minimal topical risk at typical cosmetic use levels. This is the raw botanical (dried root) form; retains the full complex of glycyrrhizin, flavonoids, chalcones, and polysaccharides; typically used as a starting material for further processing
Regulatory Flags
Frequently Asked Questions
Is Glycyrrhiza Glabra Root safe in cosmetics?
Same glycyrrhizic acid concerns as other licorice derivatives; minimal topical risk at typical cosmetic use levels. This is the raw botanical (dried root) form; retains the full complex of glycyrrhizin, flavonoids, chalcones, and polysaccharides; typically used as a starting material for further processing The EU classifies Glycyrrhiza Glabra Root as "permitted". Safety rating: MODERATE. 1 toxicological study endpoint(s) are available in our database.
Is Glycyrrhiza Glabra Root allowed in the EU?
Glycyrrhiza Glabra Root EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Glycyrrhiza Glabra Root do in cosmetics?
Glycyrrhiza Glabra Root functions as: Skin Conditioning. It is classified as a cosmetic ingredient in our database. CAS number: 68916-91-6.
What is the Margin of Safety for Glycyrrhiza Glabra Root?
not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
What is the NOAEL for Glycyrrhiza Glabra Root?
The NOAEL (No Observed Adverse Effect Level) for Glycyrrhiza Glabra Root is 1500 mg/kg bw/day based on a Short Term Toxicity study via oral route in rat. Source: COSMOS_DB.
Compliance Tools
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Related Ingredients
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