Guaiacum Officinale Wood Oil
INCI: GUAIACUM OFFICINALE WOOD OIL
Regulatory Status
For full compliance data across 55 jurisdictions, use the Substance Compliance tool.
Safety Data
Calculate MoS for your specific formulation with the MoS Calculator.
Toxicological Studies
1 study endpoint found for Guaiacum Officinale Wood Oil. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.
| Endpoint | Value | Route | Species | Study Type | Source |
|---|---|---|---|---|---|
| NOAEL | 31 mg/kg bw/day | oral | rat | Subchronic | COSMOS_DB |
Expert Verdict
CITES Appendix II species requiring full traceability; related guaiacwood acetate exhibits phototoxicity with NOEL of 6% and maximum safe use of 1.2%; batch-to-batch compositional variability and limited standalone safety data warrant cautious use.
Regulatory Flags
Frequently Asked Questions
Is Guaiacum Officinale Wood Oil safe in cosmetics?
CITES Appendix II species requiring full traceability; related guaiacwood acetate exhibits phototoxicity with NOEL of 6% and maximum safe use of 1.2%; batch-to-batch compositional variability and limited standalone safety data warrant cautious use. The EU classifies Guaiacum Officinale Wood Oil as "permitted". Safety rating: MODERATE. 1 toxicological study endpoint(s) are available in our database.
Is Guaiacum Officinale Wood Oil allowed in the EU?
Guaiacum Officinale Wood Oil EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Guaiacum Officinale Wood Oil do in cosmetics?
Guaiacum Officinale Wood Oil functions as: Fragrance ingredient. It is classified as a cosmetic ingredient in our database. CAS number: 8016-23-7.
What is the Margin of Safety for Guaiacum Officinale Wood Oil?
not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
What is the NOAEL for Guaiacum Officinale Wood Oil?
The NOAEL (No Observed Adverse Effect Level) for Guaiacum Officinale Wood Oil is 31 mg/kg bw/day based on a Subchronic study via oral route in rat. Source: COSMOS_DB.
Compliance Tools
Check Guaiacum Officinale Wood Oil compliance across multiple jurisdictions:
Related Ingredients
Is Guaiacum Officinale Wood Oil in Your Products?
Scan any product label with Piro — our free ingredient scanner. Point your camera at the ingredients list and get instant safety scores for every ingredient.
Try Piro Free →Analyze Your Full Ingredient List
Paste any INCI list into the Decoder for instant safety analysis, or calculate the Margin of Safety for Guaiacum Officinale Wood Oil in your formulation.