Regulatory Status
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Safety Data
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Expert Verdict
Cysteamine-derived ingredients are subject to increasing regulatory scrutiny. The HBr counterion is unusual — bromide accumulation should be ruled out for leave-on use. Requires sensitization, irritation, and percutaneous absorption studies. Read-across from cysteamine HCl SCCS opinion may partially apply.
Regulatory Flags
Frequently Asked Questions
Is Guanylcystamine HBr safe in cosmetics?
Cysteamine-derived ingredients are subject to increasing regulatory scrutiny. The HBr counterion is unusual — bromide accumulation should be ruled out for leave-on use. Requires sensitization, irritation, and percutaneous absorption studies. Read-across from cysteamine HCl SCCS opinion may partially apply. The EU classifies Guanylcystamine HBr as "permitted". Safety rating: MODERATE.
Is Guanylcystamine HBr allowed in the EU?
Guanylcystamine HBr EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Guanylcystamine HBr do in cosmetics?
Guanylcystamine HBr functions as: Skin conditioning (guanidine-cysteamine conjugate, hydrobromide salt). It is classified as a cosmetic ingredient in our database. CAS number: Not readily available.
What is the Margin of Safety for Guanylcystamine HBr?
not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
Compliance Tools
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Related Ingredients
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