Harpagoside

INCI: HARPAGOSIDE

CAS Number
19210-12-9
Function
Skin conditioning (iridoid glycoside from Harpagophytum procumbens)
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Permitted โ€” no specific CFR prohibition

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Data gaps exist in safety profile; toxicological information largely based on default statements with no CIR/SCCS review available.

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Concern Level: Moderate

Frequently Asked Questions

Is Harpagoside safe in cosmetics?

Data gaps exist in safety profile; toxicological information largely based on default statements with no CIR/SCCS review available. The EU classifies Harpagoside as "permitted". Safety rating: MODERATE.

Is Harpagoside allowed in the EU?

Harpagoside EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Harpagoside do in cosmetics?

Harpagoside functions as: Skin conditioning (iridoid glycoside from Harpagophytum procumbens). It is classified as a cosmetic ingredient in our database. CAS number: 19210-12-9.

What is the Margin of Safety for Harpagoside?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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