Is HC Red No. 10 safe in cosmetics?
HC Red No. 10 has a safety rating of "MODERATE" in our database. EU status: restricted. US status: permitted.
HC Red No. 10
INCI: HC RED NO. 10
HC Red No. 10 (CAS Verify against current CosIng - chemical names listed include 1-Amino-2-nitro-4-(2',3'-dihydroxypropyl)amino-5-chlorobenzene and 1,4-Bis-(2',3'-dihydroxypropyl)amino-2-nitro-5-chlorobenzene) is a cosmetic cosmetic ingredient functioning as Hair dyeing (direct/semi-permanent dye). EU Regulation 1223/2009 status: restricted. Industrial safety data is also available in the chemical safety database.
Auto-generated CPSR Part A draft with source citations
CAS Number
Verify against current CosIng - chemical names listed include 1-Amino-2-nitro-4-(2',3'-dihydroxypropyl)amino-5-chlorobenzene and 1,4-Bis-(2',3'-dihydroxypropyl)amino-2-nitro-5-chlorobenzene
View industrial chemical safety profile →
Function
Hair dyeing (direct/semi-permanent dye)
Safety Rating
MODERATE
Regulatory Status
EU EU Status
restricted
US US Status
permitted
US Notes
Falls under the coal tar hair dye exemption; permitted with caution labeling and patch test advisory
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for HC Red No. 10.
Calculate MoS for your specific formulation with the MoS Calculator.
Sensitization Profile
Contact sensitization data for HC Red No. 10 based on clinical patch test studies and IFRA standards.
Sensitization Rate
low
Allergen Class
dye
EU Allergen Listed
no
Patch Test Positive Rate
0.2%
Cross-reactivity Group
para-amino-group
Reaction Type
contact-dermatitis
Source: SCCS; IVDK
Additional Ingredient Properties
2 property records from structured ingredient metadata.
allergen_detail
{"eu_allergen_listed": "no", "allergen_class": "dye", "cross_reactivity_group": "para-amino-group", "patch_test_frequency_pct": "0.2", "sensitization_rate": "low", "common_reaction_type": "contact-dermatitis", "ifra_restricted": "no", "source": "SCCS; IVDK"}
hair_dye
{"cas_number": "95576-89-9", "ingredient_class": "direct_dye", "chemical_class": "nitro", "molecular_weight_Da": "168.15", "color_result_on_hair": "Red", "shade_range": "red", "primary_function": "direct_deposit", "requires_developer": "no", "lift_capability_levels": "0", "deposit_only": "yes", "permanence": "semi_permanent", "wash_fastness_shampoos": "6-12", "light_fastness": "moderate", "heat_st…
Expert Verdict
Expert safety assessment and concern-level summary for HC Red No. 10.
Regulatory Flags
potential-allergen
NOAEL Studies Summary
View details ->Public NOAEL study rows linked to HC Red No. 10 by CAS number or substance name.
Studies
44
Lowest NOAEL
0.0006
Highest NOAEL
100
Units vary across source rows: mg/kg bw, mg/kg bw/d
SCCS_vision_codex
Frequently Asked Questions
Is HC Red No. 10 allowed in the EU?
HC Red No. 10 EU regulatory status: restricted. This is based on EU Regulation 1223/2009 and its amendments.
What does HC Red No. 10 do in cosmetics?
HC Red No. 10 functions as: Hair dyeing (direct/semi-permanent dye). It is classified as a cosmetic ingredient in our database. CAS number: Verify against current CosIng - chemical names listed include 1-Amino-2-nitro-4-(2',3'-dihydroxypropyl)amino-5-chlorobenzene and 1,4-Bis-(2',3'-dihydroxypropyl)amino-2-nitro-5-chlorobenzene.
Compliance Tools
Check HC Red No. 10 compliance across multiple jurisdictions:
Ingredient Decoder
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82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
Check compliance across multiple jurisdictions
MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
Compare limits across jurisdictions
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