Moderate Cosmetic Ingredient SCCS/CIR Reviewed Sensitization Data

HC Yellow No. 5

INCI: HC YELLOW NO. 5

CAS Number
56932-44-6
Function
Hair Dyeing (non-oxidative / oxidative)
Safety Rating
MODERATE

Regulatory Status

🇪🇺 EU Status prohibited
🇺🇸 US Status permitted
US Notes Unapproved color additive; permitted under coal-tar hair dye exemption only; CIR concluded safe as hair dye ingredient

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
low
Sensitization
moderate

Calculate MoS for your specific formulation with the MoS Calculator.

Safety Opinions

Official safety assessments from the Scientific Committee on Consumer Safety (SCCS) and Cosmetic Ingredient Review (CIR).

cir 30 November 2006
Verdict: unknown

Sensitization Profile

Contact sensitization data for HC Yellow No. 5 based on clinical patch test studies and IFRA standards.

Sensitization Rate
low
Allergen Class
dye
EU Allergen Listed
no
Patch Test Positive Rate
0.2%
Cross-reactivity Group
para-amino-group
Reaction Type
contact-dermatitis

Source: SCCS; IVDK

Expert Verdict

EU-banned ingredient cannot be used in any cosmetic product marketed in the EU; oral LD50 555.56 mg/kg (rat); skin irritation potential

⚠️
Concern Level: High

Regulatory Flags

eu_banned_cosmetics eu_cosing_listed

Frequently Asked Questions

Is HC Yellow No. 5 safe in cosmetics?

EU-banned ingredient cannot be used in any cosmetic product marketed in the EU; oral LD50 555.56 mg/kg (rat); skin irritation potential The EU classifies HC Yellow No. 5 as "prohibited". Safety rating: MODERATE. This ingredient has been reviewed by cir.

Is HC Yellow No. 5 allowed in the EU?

HC Yellow No. 5 EU regulatory status: prohibited. This is based on EU Regulation 1223/2009 and its amendments.

What does HC Yellow No. 5 do in cosmetics?

HC Yellow No. 5 functions as: Hair Dyeing (non-oxidative / oxidative). It is classified as a cosmetic ingredient in our database. CAS number: 56932-44-6.

What is the Margin of Safety for HC Yellow No. 5?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

Compliance Tools

Check HC Yellow No. 5 compliance across multiple jurisdictions:

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Ingredient Decoder
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82 Allergen Checker
Check for EU declarable fragrance allergens
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Substance Compliance
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MoS Calculator
Calculate Margin of Safety using SCCS methodology
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Heavy Metal Limits
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