Is HC Yellow No. 5 safe in cosmetics?
HC Yellow No. 5 has a safety rating of "MODERATE" in our database. EU status: prohibited. US status: permitted. This ingredient has been reviewed by cir.
HC Yellow No. 5
Also known as: EINECS 260-450-0, N'-(2-Hydroxyethyl)-4-nitro-ortho-phenylenediamine, UNII-I844A312T7
INCI: HC YELLOW NO. 5
HC Yellow No. 5 (CAS 56932-44-6) is a cosmetic cosmetic ingredient functioning as Hair Dyeing (non-oxidative / oxidative). EU Regulation 1223/2009 status: prohibited; 1 safety opinion reviewed (cir). Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety data.
View industrial chemical safety profile for CAS 56932-44-6 →
Auto-generated CPSR Part A draft with source citations
Cross-Vertical Regulatory Divergence
HC Yellow No. 5 is prohibited in EU cosmetics but has active industrial GHS classifications (H302, H315, H319, H335).
Source: Cosmetics: ingredients.eu_status; Chemicals: ghs_classifications.signal_word/hazard_statement_code
Function
Hair Dyeing (non-oxidative / oxidative)
Safety Rating
MODERATE
Chemistry & Identifiers
IUPAC Name
2-(2-amino-4-nitroanilino)ethanol
InChIKey
OWMQBFHMJVSJSA-UHFFFAOYSA-N
Regulatory Status
EU EU Status
prohibited
US US Status
permitted
US Notes
Unapproved color additive; permitted under coal-tar hair dye exemption only; CIR concluded safe as hair dye ingredient
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for HC Yellow No. 5.
Calculate MoS for your specific formulation with the MoS Calculator.
Safety Opinions
Official safety assessments from the Scientific Committee on Consumer Safety (SCCS) and Cosmetic Ingredient Review (CIR).
cir
30 November 2006
Verdict: unknown
Sensitization Profile
Contact sensitization data for HC Yellow No. 5 based on clinical patch test studies and IFRA standards.
Sensitization Rate
low
Allergen Class
dye
EU Allergen Listed
no
Patch Test Positive Rate
0.2%
Cross-reactivity Group
para-amino-group
Reaction Type
contact-dermatitis
Source: SCCS; IVDK
EU CosIng Annex Listing
European Commission CosIng database Annex references per Regulation (EC) No 1223/2009.
Annex II — Prohibited
Ref: 1285
(EC) 2009/1223
Expanded Jurisdictional Detail
Additional regulatory detail beyond the 7-jurisdiction summary: Saudi SFDA, Korea MFDS, ASEAN ACD, Japan/Korea, Brazil/India, and cross-jurisdictional restriction entries.
SA Saudi SFDA (II - Prohibited)
ASEAN Cosmetic Directive (II)
Ref: 1285
BRIN Brazil/India Cosmetics
Brazil: Prohibited
India: Prohibited (GNRAS)
Additional Jurisdictional Restrictions (1)
| Jurisdiction | Status | Max % | Product Type |
|---|---|---|---|
| KR | prohibited | - | - |
Additional Ingredient Properties
1 property record from structured ingredient metadata.
allergen_detail
{"eu_allergen_listed": "no", "allergen_class": "dye", "cross_reactivity_group": "para-amino-group", "patch_test_frequency_pct": "0.2", "sensitization_rate": "low", "common_reaction_type": "contact-dermatitis", "ifra_restricted": "no", "source": "SCCS; IVDK"}
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Dye
Regulatory List Membership (2)
EU Banned in Cosmetics
EU CosIng Cosmetics Ingredient Database
Expert Verdict
Expert safety assessment and concern-level summary for HC Yellow No. 5.
Regulatory Flags
eu_banned_cosmetics
eu_cosing_listed
Known Synonyms
EINECS 260-450-0
N'-(2-Hydroxyethyl)-4-nitro-ortho-phenylenediamine
UNII-I844A312T7
Chemical Function
Dye
Regulatory Lists
banned; Europe; Personal care
Europe; Personal care - hair coloring
Australian Status
AICIS status: listed
Frequently Asked Questions
Is HC Yellow No. 5 allowed in the EU?
HC Yellow No. 5 EU regulatory status: prohibited. This is based on EU Regulation 1223/2009 and its amendments.
What does HC Yellow No. 5 do in cosmetics?
HC Yellow No. 5 functions as: Hair Dyeing (non-oxidative / oxidative). It is classified as a cosmetic ingredient in our database. CAS number: 56932-44-6.
Is HC Yellow No. 5 used outside cosmetics?
HC Yellow No. 5 also appears in industrial chemical safety data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Does HC Yellow No. 5 have different safety status in cosmetics vs industrial chemicals?
HC Yellow No. 5 is prohibited in EU cosmetics but has active industrial GHS classifications (H302, H315, H319, H335).
Compliance Tools
Check HC Yellow No. 5 compliance across multiple jurisdictions:
Ingredient Decoder
Paste a full ingredient list for instant analysis
82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
Check compliance across multiple jurisdictions
MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
Compare limits across jurisdictions
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