Regulatory Status
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Safety Data
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Expert Verdict
GHS Warning H302 (harmful if swallowed); haemolytic saponin with dermal use tolerable only at low concentrations but oral toxicity raises concerns; not a standard cosmetic-grade ingredient; full toxicological justification including NOAEL derivation and margin of safety calculation required for regulatory approval.
Frequently Asked Questions
Is Hederacolchiside safe in cosmetics?
GHS Warning H302 (harmful if swallowed); haemolytic saponin with dermal use tolerable only at low concentrations but oral toxicity raises concerns; not a standard cosmetic-grade ingredient; full toxicological justification including NOAEL derivation and margin of safety calculation required for regulatory approval. The EU classifies Hederacolchiside as "prohibited". Safety rating: MODERATE.
Is Hederacolchiside allowed in the EU?
Hederacolchiside EU regulatory status: prohibited. This is based on EU Regulation 1223/2009 and its amendments.
What does Hederacolchiside do in cosmetics?
Hederacolchiside functions as: Skin conditioning agent; isolated phytochemical from Hedera spp.. It is classified as a cosmetic ingredient in our database. CAS number: 106577-39-3 (Hederacolchiside A1).
What is the Margin of Safety for Hederacolchiside?
not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
Compliance Tools
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Related Ingredients
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