Heptapeptide-45

INCI: HEPTAPEPTIDE-45

CAS Number
Not assigned / not publicly available
Function
Astringent, bleaching, humectant, skin conditioning, emollient
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Permitted โ€” no CFR restriction

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
negligible
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Bleaching function may trigger drug classification in the US if skin lightening is claimed; requires melanocyte toxicity safety endpoints; no published toxicology data available.

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Concern Level: High

Frequently Asked Questions

Is Heptapeptide-45 safe in cosmetics?

Bleaching function may trigger drug classification in the US if skin lightening is claimed; requires melanocyte toxicity safety endpoints; no published toxicology data available. The EU classifies Heptapeptide-45 as "permitted". Safety rating: MODERATE.

Is Heptapeptide-45 allowed in the EU?

Heptapeptide-45 EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Heptapeptide-45 do in cosmetics?

Heptapeptide-45 functions as: Astringent, bleaching, humectant, skin conditioning, emollient. It is classified as a cosmetic ingredient in our database. CAS number: Not assigned / not publicly available.

What is the Margin of Safety for Heptapeptide-45?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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