Heptapeptide-7

INCI: HEPTAPEPTIDE-7

CAS Number
Not assigned / proprietary
Function
Skin conditioning — wound healing, keratinocyte proliferation, EGF-like activity; derived from HB-107 fragment of Cecropin B
Safety Rating
MODERATE

Regulatory Status

🇪🇺 EU Status permitted
🇺🇸 US Status permitted
US Notes Permitted — no FDA prohibition; not individually CIR-reviewed

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Small clinical dataset (n=32); no HRIPT; murine-derived peptide sequence (Cecropin B origin) with theoretical immunogenicity concern at high concentrations; no genotox or repeat-dose data published

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Concern Level: Moderate

Frequently Asked Questions

Is Heptapeptide-7 safe in cosmetics?

Small clinical dataset (n=32); no HRIPT; murine-derived peptide sequence (Cecropin B origin) with theoretical immunogenicity concern at high concentrations; no genotox or repeat-dose data published The EU classifies Heptapeptide-7 as "permitted". Safety rating: MODERATE.

Is Heptapeptide-7 allowed in the EU?

Heptapeptide-7 EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Heptapeptide-7 do in cosmetics?

Heptapeptide-7 functions as: Skin conditioning — wound healing, keratinocyte proliferation, EGF-like activity; derived from HB-107 fragment of Cecropin B. It is classified as a cosmetic ingredient in our database. CAS number: Not assigned / proprietary.

What is the Margin of Safety for Heptapeptide-7?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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