Is Heptapeptide-7 safe in cosmetics?
Heptapeptide-7 has a safety rating of "MODERATE" in our database. EU status: permitted. US status: permitted.
Moderate
Cosmetic Ingredient
Heptapeptide-7
INCI: HEPTAPEPTIDE-7
Heptapeptide-7 (CAS Not assigned / proprietary) is a cosmetic cosmetic ingredient functioning as Skin conditioning — wound healing, keratinocyte proliferation, EGF-like. EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database.
View industrial chemical safety profile for CAS Not assigned / proprietary →
Auto-generated CPSR Part A draft with source citations
Function
Skin conditioning — wound healing, keratinocyte proliferation, EGF-like activity; derived from HB-107 fragment of Cecropin B
Safety Rating
MODERATE
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
Permitted — no FDA prohibition; not individually CIR-reviewed
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Heptapeptide-7.
Calculate MoS for your specific formulation with the MoS Calculator.
Additional Ingredient Properties
2 property records from structured ingredient metadata.
anti_pollution
{"cas_number": "223749-133-0", "ingredient_class": "other", "primary_mechanism": "barrier_reinforcement", "pollution_types_targeted": "PM2_5", "IR_A_protection": "no", "visible_light_protection": "no", "digital_screen_protection_claim": "no", "PAH_neutralization": "no", "ozone_protection": "no", "mitochondrial_protection": "no", "Nrf2_activation": "no", "AhR_pathway_modulation": "no", "NF_kB_inhib…
self_tanning
{"cas_number": "proprietary", "ingredient_class": "tan_accelerator", "tanning_mechanism": "melanin_stimulation", "color_development_onset_hours": "0.0", "full_color_development_hours": "0", "color_duration_days": "0", "DHA_concentration_if_applicable_pct": "0", "erythrulose_concentration_pct": "0", "pH_dependent_color": "no", "formaldehyde_release_concern": "no", "formaldehyde_release_ppm": "0", "…
Expert Verdict
Expert safety assessment and concern-level summary for Heptapeptide-7.
Frequently Asked Questions
Is Heptapeptide-7 allowed in the EU?
Heptapeptide-7 EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Heptapeptide-7 do in cosmetics?
Heptapeptide-7 functions as: Skin conditioning — wound healing, keratinocyte proliferation, EGF-like activity; derived from HB-107 fragment of Cecropin B. It is classified as a cosmetic ingredient in our database. CAS number: Not assigned / proprietary.
Compliance Tools
Check Heptapeptide-7 compliance across multiple jurisdictions:
Ingredient Decoder
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82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
Check compliance across multiple jurisdictions
MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
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