Is Heptyl Formate safe in cosmetics?
Heptyl Formate has a safety rating of "GOOD" in our database. EU status: permitted. US status: permitted.
Good
Cosmetic Ingredient
Heptyl Formate
Also known as: BRN 1750248, EINECS 203-949-0, FEMA No. 2552, Heptanol, formate, Heptyl alcohol formate (+3 more)
INCI: HEPTYL FORMATE
Heptyl Formate (CAS 112-23-2) is a cosmetic cosmetic ingredient functioning as Fragrance / flavoring agent with fruity aroma. EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety and pharmaceutical data.
View industrial chemical safety profile for CAS 112-23-2 →
Auto-generated CPSR Part A draft with source citations
Cross-Vertical Regulatory Divergence
Heptyl Formate is classified GHS Danger (H226, H315, H318, H319) in the chemicals database but is allowed in EU cosmetics.
Source: Cosmetics: ingredients.eu_status; Chemicals: ghs_classifications.signal_word/hazard_statement_code
Function
Fragrance / flavoring agent with fruity aroma
Safety Rating
GOOD
Chemistry & Identifiers
IUPAC Name
heptyl formate
InChIKey
XEAMDSXSXYAICO-UHFFFAOYSA-N
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
Permitted — FEMA GRAS
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Heptyl Formate.
Calculate MoS for your specific formulation with the MoS Calculator.
HRIPT Human Patch Test Studies
1 human repeat insult patch test aggregated from dermatological literature.
| Test Type | N | Sensitized | Dose µg/cm² | NESIL µg/cm² | Potency |
|---|---|---|---|---|---|
| HMT | - | 0 | 8100 | - | - |
PubChem Annotations
Safety and regulatory annotations from PubChem (NCBI) aggregated sources.
Regulatory (2)
JECFA Number
121
Source: Joint FAO/WHO Expert Committee on Food Additives (JECFA)
JECFA Evaluation
HEPTYL FORMATE | 1997 | No safety concern at current levels of intake when used as a flavouring agent | TRS 884-JECFA 49/52 | FAS 40-JECFA 49/297
Source: Joint FAO/WHO Expert Committee on Food Additives (JECFA)
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Flavouring and nutrient
Fragrance
Regulatory List Membership (1)
FDA Substances Added to Food (EAFUS)
Expert Verdict
Expert safety assessment and concern-level summary for Heptyl Formate.
Regulatory Flags
fragrance-component
fda_food_additive
jecfa_safe
Known Synonyms
BRN 1750248
EINECS 203-949-0
FEMA No. 2552
Heptanol, formate
Heptyl alcohol formate
n-Heptyl methanoate
Heptyl methanote
UNII-PU6O623G48
Chemical Function
Fragrance
Flavouring and nutrient
Regulatory Lists
Europe
food_additive; Substances Added to Food (formerly EAFUS) (2/2019)
Australian Status
AICIS status: listed
Cross-Vertical Safety Context
Same-CAS public records found in pharmaceutical data.
SOURCE
ChEMBL / DrugCentral / FAERS
DB_PHARMA CAS match
Pharmaceutical Data
Same-CAS rows from the pharmaceutical spoke database.
Compound
HEPTYL FORMATE
ChEMBL ID
CHEMBL2270392
Frequently Asked Questions
Is Heptyl Formate allowed in the EU?
Heptyl Formate EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Heptyl Formate do in cosmetics?
Heptyl Formate functions as: Fragrance / flavoring agent with fruity aroma. It is classified as a cosmetic ingredient in our database. CAS number: 112-23-2.
Is Heptyl Formate used outside cosmetics?
Heptyl Formate also appears in industrial chemical safety and pharmaceutical data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Does Heptyl Formate have different safety status in cosmetics vs industrial chemicals?
Heptyl Formate is classified GHS Danger (H226, H315, H318, H319) in the chemicals database but is allowed in EU cosmetics.
Compliance Tools
Check Heptyl Formate compliance across multiple jurisdictions:
Ingredient Decoder
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82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
Check compliance across multiple jurisdictions
MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
Compare limits across jurisdictions
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