Heracleum Moellendorffii Leaf Extract

INCI: HERACLEUM MOELLENDORFFII LEAF EXTRACT

CAS Number
Not assigned (botanical extract)
Function
Skin conditioning; anti-melanogenic (tyrosinase inhibition via ERK1/2 pathway)
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status restricted
๐Ÿ‡บ๐Ÿ‡ธ US Status restricted
US Notes Permitted - not specifically restricted under 21 CFR

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
moderate

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Furocoumarin risk: genus produces psoralen, bergapten, 5-MOP, 8-MOP; must quantify total furocoumarins and confirm <1 ppm (sun products) or <5 ppm (other cosmetics) per EU guidance; phototoxicity testing recommended

โš ๏ธ
Concern Level: High

Regulatory Flags

plant-extract

Frequently Asked Questions

Is Heracleum Moellendorffii Leaf Extract safe in cosmetics?

Furocoumarin risk: genus produces psoralen, bergapten, 5-MOP, 8-MOP; must quantify total furocoumarins and confirm <1 ppm (sun products) or <5 ppm (other cosmetics) per EU guidance; phototoxicity testing recommended The EU classifies Heracleum Moellendorffii Leaf Extract as "restricted". Safety rating: MODERATE.

Is Heracleum Moellendorffii Leaf Extract allowed in the EU?

Heracleum Moellendorffii Leaf Extract EU regulatory status: restricted. This is based on EU Regulation 1223/2009 and its amendments.

What does Heracleum Moellendorffii Leaf Extract do in cosmetics?

Heracleum Moellendorffii Leaf Extract functions as: Skin conditioning; anti-melanogenic (tyrosinase inhibition via ERK1/2 pathway). It is classified as a cosmetic ingredient in our database. CAS number: Not assigned (botanical extract).

What is the Margin of Safety for Heracleum Moellendorffii Leaf Extract?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

๐Ÿ“ฑ

Is Heracleum Moellendorffii Leaf Extract in Your Products?

Scan any product label with Piro โ€” our free ingredient scanner. Point your camera at the ingredients list and get instant safety scores for every ingredient.

Try Piro Free โ†’

Analyze Your Full Ingredient List

Paste any INCI list into the Decoder for instant safety analysis, or calculate the Margin of Safety for Heracleum Moellendorffii Leaf Extract in your formulation.