Is Hexahydro-benzofuranone safe in cosmetics?
Hexahydro-benzofuranone has a safety rating of "GOOD" in our database. EU status: permitted. US status: permitted.
Good
Cosmetic Ingredient
Hexahydro-benzofuranone
Also known as: Cyclohexaneacetic acid, 2-hydroxy-, gamma-lactone, 2(3H)-Benzofuranone, hexahydro-, EINECS 227-955-8, NSC 127884
Hexahydro-benzofuranone (CAS 6051-03-2) is a cosmetic cosmetic ingredient functioning as Fragrance. EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety data.
View industrial chemical safety profile for CAS 6051-03-2 →
Auto-generated CPSR Part A draft with source citations
Function
Fragrance
Safety Rating
GOOD
Chemistry & Identifiers
IUPAC Name
3a,4,5,6,7,7a-hexahydro-3H-1-benzofuran-2-one
InChIKey
AQKZNTBBGPQPBG-UHFFFAOYSA-N
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
Permitted — no specific CFR restriction
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Hexahydro-benzofuranone.
Calculate MoS for your specific formulation with the MoS Calculator.
HRIPT Human Patch Test Studies
1 human repeat insult patch test aggregated from dermatological literature.
| Test Type | N | Sensitized | Dose µg/cm² | NESIL µg/cm² | Potency |
|---|---|---|---|---|---|
| HRIPT | - | 0 | 1938 | - | - |
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Fragrance
Regulatory List Membership (2)
IFRA Fragrance Transparency List
Consumer Product Chemical
Expert Verdict
Expert safety assessment and concern-level summary for Hexahydro-benzofuranone.
Regulatory Flags
fragrance-component
ifra_fragrance
Known Synonyms
Cyclohexaneacetic acid, 2-hydroxy-, gamma-lactone
2(3H)-Benzofuranone, hexahydro-
EINECS 227-955-8
NSC 127884
Chemical Function
Fragrance
Regulatory Lists
IFRA Transparency
consumer_product
Australian Status
AICIS status: listed
Frequently Asked Questions
Is Hexahydro-benzofuranone allowed in the EU?
Hexahydro-benzofuranone EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Hexahydro-benzofuranone do in cosmetics?
Hexahydro-benzofuranone functions as: Fragrance. It is classified as a cosmetic ingredient in our database. CAS number: 6051-03-2.
Is Hexahydro-benzofuranone used outside cosmetics?
Hexahydro-benzofuranone also appears in industrial chemical safety data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Compliance Tools
Check Hexahydro-benzofuranone compliance across multiple jurisdictions:
Ingredient Decoder
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82 Allergen Checker
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Substance Compliance
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MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
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