Hexahydro-Tetramethyl-Benzopyran

INCI: HEXAHYDRO-TETRAMETHYL-BENZOPYRAN

CAS Number
72429-08-4
Function
Fragrance (musky/amber/woody)
Safety Rating
GOOD

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Permitted โ€” not specifically restricted under 21 CFR 700

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
low
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Not genotoxic or phototoxic/photoallergenic; safety relies on TTC approach with Cramer Class III conservative thresholds due to lack of NOAEL data for repeated dose and reproductive endpoints.

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Concern Level: Moderate

Regulatory Flags

potential-allergen fragrance-component ifra_fragrance

Frequently Asked Questions

Is Hexahydro-Tetramethyl-Benzopyran safe in cosmetics?

Not genotoxic or phototoxic/photoallergenic; safety relies on TTC approach with Cramer Class III conservative thresholds due to lack of NOAEL data for repeated dose and reproductive endpoints. The EU classifies Hexahydro-Tetramethyl-Benzopyran as "permitted". Safety rating: GOOD.

Is Hexahydro-Tetramethyl-Benzopyran allowed in the EU?

Hexahydro-Tetramethyl-Benzopyran EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Hexahydro-Tetramethyl-Benzopyran do in cosmetics?

Hexahydro-Tetramethyl-Benzopyran functions as: Fragrance (musky/amber/woody). It is classified as a cosmetic ingredient in our database. CAS number: 72429-08-4.

What is the Margin of Safety for Hexahydro-Tetramethyl-Benzopyran?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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