Hexamethylene Bis-hydroxystearamide
INCI: HEXAMETHYLENE BIS-HYDROXYSTEARAMIDE
Regulatory Status
For full compliance data across 55 jurisdictions, use the Substance Compliance tool.
Safety Data
Calculate MoS for your specific formulation with the MoS Calculator.
Toxicological Studies
2 study endpoints found for Hexamethylene Bis-hydroxystearamide. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.
| Endpoint | Value | Route | Species | Study Type | Source |
|---|---|---|---|---|---|
| NOAEL | >=1000 mg/kg bw/day | oral | rat | oral | REACH |
| NOAEL | >=1000 mg/kg bw/day | oral | - | oral | REACH |
Expert Verdict
H317 skin sensitization flag (25.2% of notifications) and H413 aquatic chronic toxicity flag (33.7%); no CIR or SCCS full review identified; batch-dependent impurity profiles may influence sensitization potential.
Regulatory Flags
Frequently Asked Questions
Is Hexamethylene Bis-hydroxystearamide safe in cosmetics?
H317 skin sensitization flag (25.2% of notifications) and H413 aquatic chronic toxicity flag (33.7%); no CIR or SCCS full review identified; batch-dependent impurity profiles may influence sensitization potential. The EU classifies Hexamethylene Bis-hydroxystearamide as "permitted". Safety rating: MODERATE. 2 toxicological study endpoint(s) are available in our database.
Is Hexamethylene Bis-hydroxystearamide allowed in the EU?
Hexamethylene Bis-hydroxystearamide EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Hexamethylene Bis-hydroxystearamide do in cosmetics?
Hexamethylene Bis-hydroxystearamide functions as: Hair conditioning, humectant, skin conditioning. It is classified as a cosmetic ingredient in our database. CAS number: 55349-01-4.
What is the Margin of Safety for Hexamethylene Bis-hydroxystearamide?
not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
What is the NOAEL for Hexamethylene Bis-hydroxystearamide?
The NOAEL (No Observed Adverse Effect Level) for Hexamethylene Bis-hydroxystearamide is >=1000 mg/kg bw/day based on a oral study via oral route in rat. A total of 2 study endpoints are available. Source: REACH.
Compliance Tools
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Related Ingredients
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