Hexanediol Dimethacrylate

INCI: 1,6-HEXANEDIOL DIMETHACRYLATE

CAS Number
6606-59-3
Function
Crosslinking agent and film former, primarily used in dental and nail applications
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Permitted with no specific 21 CFR restriction; FDA-cleared for dental devices

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
moderate
Sensitization
high

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Strong contact sensitizer and one of the most commonly reported methacrylate allergens in patch-test series; primarily used in nail products where skin contact should be minimized; unreacted monomer is the primary risk driver; complete cure and polymerization required to minimize exposure risk.

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Concern Level: High

Regulatory Flags

potential-allergen

Frequently Asked Questions

Is Hexanediol Dimethacrylate safe in cosmetics?

Strong contact sensitizer and one of the most commonly reported methacrylate allergens in patch-test series; primarily used in nail products where skin contact should be minimized; unreacted monomer is the primary risk driver; complete cure and polymerization required to minimize exposure risk. The EU classifies Hexanediol Dimethacrylate as "permitted". Safety rating: MODERATE.

Is Hexanediol Dimethacrylate allowed in the EU?

Hexanediol Dimethacrylate EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Hexanediol Dimethacrylate do in cosmetics?

Hexanediol Dimethacrylate functions as: Crosslinking agent and film former, primarily used in dental and nail applications. It is classified as a cosmetic ingredient in our database. CAS number: 6606-59-3.

What is the Margin of Safety for Hexanediol Dimethacrylate?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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