Is Hexapeptide-48 HCl safe in cosmetics?
Hexapeptide-48 HCl has a safety rating of "GOOD" in our database. EU status: permitted. US status: permitted.
Good
Cosmetic Ingredient
Hexapeptide-48 HCl
INCI: HEXAPEPTIDE-48 HCL
Hexapeptide-48 HCl (CAS Not publicly assigned (trade name: Rubixyl®)) is a cosmetic cosmetic ingredient functioning as Skin conditioning; anti-inflammatory; improves epidermal differentiation and. EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database.
View industrial chemical safety profile for CAS Not publicly assigned (trade name: Rubixyl®) →
Auto-generated CPSR Part A draft with source citations
Function
Skin conditioning; anti-inflammatory; improves epidermal differentiation and barrier function
Safety Rating
GOOD
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
Permitted — not prohibited or restricted under 21 CFR; no CIR monograph
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Hexapeptide-48 HCl.
Calculate MoS for your specific formulation with the MoS Calculator.
Expert Verdict
Expert safety assessment and concern-level summary for Hexapeptide-48 HCl.
Frequently Asked Questions
Is Hexapeptide-48 HCl allowed in the EU?
Hexapeptide-48 HCl EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Hexapeptide-48 HCl do in cosmetics?
Hexapeptide-48 HCl functions as: Skin conditioning; anti-inflammatory; improves epidermal differentiation and barrier function. It is classified as a cosmetic ingredient in our database. CAS number: Not publicly assigned (trade name: Rubixyl®).
Compliance Tools
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Substance Compliance
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MoS Calculator
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Heavy Metal Limits
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