Hexyl Butyrate

INCI: HEXYL BUTYRATE

CAS Number
2639-63-6
Function
Fragrance ingredient (fruity top note modifier)
Safety Rating
GOOD

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Permitted โ€” FEMA GRAS (No. 2568); no cosmetic restriction under 21 CFR

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
low
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Hydrolysis products (hexanol, butyric acid) are well-studied with no genotoxicity structural alerts; limited specific dermal repeated-dose data available.

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Concern Level: Low

Regulatory Flags

fragrance-component ifra_fragrance fda_food_additive jecfa_safe

Frequently Asked Questions

Is Hexyl Butyrate safe in cosmetics?

Hydrolysis products (hexanol, butyric acid) are well-studied with no genotoxicity structural alerts; limited specific dermal repeated-dose data available. The EU classifies Hexyl Butyrate as "permitted". Safety rating: GOOD.

Is Hexyl Butyrate allowed in the EU?

Hexyl Butyrate EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Hexyl Butyrate do in cosmetics?

Hexyl Butyrate functions as: Fragrance ingredient (fruity top note modifier). It is classified as a cosmetic ingredient in our database. CAS number: 2639-63-6.

What is the Margin of Safety for Hexyl Butyrate?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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