Human Adipose Stromal Cell Exosomes

INCI: HUMAN ADIPOSE STROMAL CELL EXOSOMES (COSING REF NO. 94665)

CAS Number
Not assigned
Function
Skin conditioning, hair conditioning (extracellular vesicle-mediated signaling)
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status prohibited
๐Ÿ‡บ๐Ÿ‡ธ US Status prohibited
US Notes Not explicitly prohibited, but FDA has issued multiple warnings against unapproved exosome products; high regulatory risk if therapeutic claims are made

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Non-trivial pathogen transmission risk; ethical and traceability issues; blurs the cosmetic/biologic drug line; lack of standardized isolation, size confirmation, and marker validation protocols. Extracellular vesicles (30-150 nm) secreted into conditioned media by adipose-derived stromal cells; carry bioactive cargo (proteins, miRNAs, lipids); distinct from conditioned media in that they represent a purified vesicle fraction rather than the full secretome

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Concern Level: Moderate

Frequently Asked Questions

Is Human Adipose Stromal Cell Exosomes safe in cosmetics?

Non-trivial pathogen transmission risk; ethical and traceability issues; blurs the cosmetic/biologic drug line; lack of standardized isolation, size confirmation, and marker validation protocols. Extracellular vesicles (30-150 nm) secreted into conditioned media by adipose-derived stromal cells; carry bioactive cargo (proteins, miRNAs, lipids); distinct from conditioned media in that they represent a purified vesicle fraction rather than the full secretome The EU classifies Human Adipose Stromal Cell Exosomes as "prohibited". Safety rating: MODERATE.

Is Human Adipose Stromal Cell Exosomes allowed in the EU?

Human Adipose Stromal Cell Exosomes EU regulatory status: prohibited. This is based on EU Regulation 1223/2009 and its amendments.

What does Human Adipose Stromal Cell Exosomes do in cosmetics?

Human Adipose Stromal Cell Exosomes functions as: Skin conditioning, hair conditioning (extracellular vesicle-mediated signaling). It is classified as a cosmetic ingredient in our database. CAS number: Not assigned.

What is the Margin of Safety for Human Adipose Stromal Cell Exosomes?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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