Human Amniotic Fluid Mesenchymal Stem Cell/Trophoblast Cell Exosomes

INCI: HUMAN AMNIOTIC FLUID MESENCHYMAL STEM CELL/TROPHOBLAST CELL EXOSOMES

CAS Number
Not assigned
Function
Skin conditioning
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status prohibited
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Allowed with caveats - INCI registered in PCPC database (entry \#7 in PCPC exosome list); no explicit cosmetic ban but subject to general safety requirements under MoCRA

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Dual cell-source (MSC + trophoblast) increases complexity of characterization; pathogen transmission risk; lack of standardized potency testing; ethical sourcing concerns. Combines exosome cargo from two distinct cell types - mesenchymal stem cells and trophoblast cells - potentially offering a broader spectrum of growth factors and cytokines

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Concern Level: Moderate

Frequently Asked Questions

Is Human Amniotic Fluid Mesenchymal Stem Cell/Trophoblast Cell Exosomes safe in cosmetics?

Dual cell-source (MSC + trophoblast) increases complexity of characterization; pathogen transmission risk; lack of standardized potency testing; ethical sourcing concerns. Combines exosome cargo from two distinct cell types - mesenchymal stem cells and trophoblast cells - potentially offering a broader spectrum of growth factors and cytokines The EU classifies Human Amniotic Fluid Mesenchymal Stem Cell/Trophoblast Cell Exosomes as "prohibited". Safety rating: MODERATE.

Is Human Amniotic Fluid Mesenchymal Stem Cell/Trophoblast Cell Exosomes allowed in the EU?

Human Amniotic Fluid Mesenchymal Stem Cell/Trophoblast Cell Exosomes EU regulatory status: prohibited. This is based on EU Regulation 1223/2009 and its amendments.

What does Human Amniotic Fluid Mesenchymal Stem Cell/Trophoblast Cell Exosomes do in cosmetics?

Human Amniotic Fluid Mesenchymal Stem Cell/Trophoblast Cell Exosomes functions as: Skin conditioning. It is classified as a cosmetic ingredient in our database. CAS number: Not assigned.

What is the Margin of Safety for Human Amniotic Fluid Mesenchymal Stem Cell/Trophoblast Cell Exosomes?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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