Human Bone Marrow Mesenchymal Cell Culture Extract

INCI: HUMAN BONE MARROW MESENCHYMAL CELL CULTURE EXTRACT

CAS Number
Not assigned
Function
Skin conditioning
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status prohibited
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Allowed with caveats - no explicit cosmetic prohibition; extract (vs. conditioned media) implies additional processing/concentration steps; safety documentation expected under MoCRA

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Donor variability; potential for residual cellular material; pathogen risk; FBS contamination if used in culture; undefined potency standards. Distinguished from "conditioned media" by being an extract - implying concentration or selective isolation of specific bioactive fractions; contains growth factors, cytokines, and ECM components from bone marrow MSCs

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Concern Level: Moderate

Regulatory Flags

plant-extract

Frequently Asked Questions

Is Human Bone Marrow Mesenchymal Cell Culture Extract safe in cosmetics?

Donor variability; potential for residual cellular material; pathogen risk; FBS contamination if used in culture; undefined potency standards. Distinguished from "conditioned media" by being an extract - implying concentration or selective isolation of specific bioactive fractions; contains growth factors, cytokines, and ECM components from bone marrow MSCs The EU classifies Human Bone Marrow Mesenchymal Cell Culture Extract as "prohibited". Safety rating: MODERATE.

Is Human Bone Marrow Mesenchymal Cell Culture Extract allowed in the EU?

Human Bone Marrow Mesenchymal Cell Culture Extract EU regulatory status: prohibited. This is based on EU Regulation 1223/2009 and its amendments.

What does Human Bone Marrow Mesenchymal Cell Culture Extract do in cosmetics?

Human Bone Marrow Mesenchymal Cell Culture Extract functions as: Skin conditioning. It is classified as a cosmetic ingredient in our database. CAS number: Not assigned.

What is the Margin of Safety for Human Bone Marrow Mesenchymal Cell Culture Extract?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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