Human Endothelial Cell Conditioned Media

INCI: HUMAN ENDOTHELIAL CELL CONDITIONED MEDIA

CAS Number
Not established
Function
Skin conditioning (vascular growth factors — VEGF, FGF)
Safety Rating
MODERATE

Regulatory Status

🇪🇺 EU Status permitted
🇺🇸 US Status restricted
US Notes Not explicitly prohibited; requires MoCRA safety substantiation

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
moderate
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

VEGF-containing conditioned media raises theoretical angiogenesis concerns at wound sites or compromised skin barriers; lacks CIR review and established safety substantiation.

⚠️
Concern Level: Moderate

Frequently Asked Questions

Is Human Endothelial Cell Conditioned Media safe in cosmetics?

VEGF-containing conditioned media raises theoretical angiogenesis concerns at wound sites or compromised skin barriers; lacks CIR review and established safety substantiation. The EU classifies Human Endothelial Cell Conditioned Media as "permitted". Safety rating: MODERATE.

Is Human Endothelial Cell Conditioned Media allowed in the EU?

Human Endothelial Cell Conditioned Media EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Human Endothelial Cell Conditioned Media do in cosmetics?

Human Endothelial Cell Conditioned Media functions as: Skin conditioning (vascular growth factors — VEGF, FGF). It is classified as a cosmetic ingredient in our database. CAS number: Not established.

What is the Margin of Safety for Human Endothelial Cell Conditioned Media?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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