Human Neonatal Fibroblast Conditioned Media

INCI: HUMAN NEONATAL FIBROBLAST CONDITIONED MEDIA

CAS Number
Not assigned
Function
Skin conditioning — source of growth factors (TGF-β, VEGF, KGF, IL-6/8)
Safety Rating
MODERATE

Regulatory Status

🇪🇺 EU Status permitted
🇺🇸 US Status permitted
US Notes Permitted; most commercially established of the group (e.g., used in marketed US products)

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Mitogenic potential presents risk for skin cancer and may contraindicate use in psoriasis; batch variability and lack of standardized composition limit safety assessment; fetal bovine serum residuals possible in culture medium.

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Concern Level: High

Frequently Asked Questions

Is Human Neonatal Fibroblast Conditioned Media safe in cosmetics?

Mitogenic potential presents risk for skin cancer and may contraindicate use in psoriasis; batch variability and lack of standardized composition limit safety assessment; fetal bovine serum residuals possible in culture medium. The EU classifies Human Neonatal Fibroblast Conditioned Media as "permitted". Safety rating: MODERATE.

Is Human Neonatal Fibroblast Conditioned Media allowed in the EU?

Human Neonatal Fibroblast Conditioned Media EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Human Neonatal Fibroblast Conditioned Media do in cosmetics?

Human Neonatal Fibroblast Conditioned Media functions as: Skin conditioning — source of growth factors (TGF-β, VEGF, KGF, IL-6/8). It is classified as a cosmetic ingredient in our database. CAS number: Not assigned.

What is the Margin of Safety for Human Neonatal Fibroblast Conditioned Media?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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