Human Neonatal Fibroblast/Keratinocyte Conditioned Media

INCI: HUMAN NEONATAL FIBROBLAST/KERATINOCYTE CONDITIONED MEDIA

CAS Number
Not assigned
Function
Skin conditioning — broader growth factor profile from dual cell culture
Safety Rating
MODERATE

Regulatory Status

🇪🇺 EU Status permitted
🇺🇸 US Status permitted
US Notes Permitted (no specific CFR prohibition)

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
moderate

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Dual cell culture conditioned media with variable growth factor profile; keratinocyte-derived factors may include pro-inflammatory cytokines; batch standardization presents additional regulatory challenge.

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Concern Level: Moderate

Frequently Asked Questions

Is Human Neonatal Fibroblast/Keratinocyte Conditioned Media safe in cosmetics?

Dual cell culture conditioned media with variable growth factor profile; keratinocyte-derived factors may include pro-inflammatory cytokines; batch standardization presents additional regulatory challenge. The EU classifies Human Neonatal Fibroblast/Keratinocyte Conditioned Media as "permitted". Safety rating: MODERATE.

Is Human Neonatal Fibroblast/Keratinocyte Conditioned Media allowed in the EU?

Human Neonatal Fibroblast/Keratinocyte Conditioned Media EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Human Neonatal Fibroblast/Keratinocyte Conditioned Media do in cosmetics?

Human Neonatal Fibroblast/Keratinocyte Conditioned Media functions as: Skin conditioning — broader growth factor profile from dual cell culture. It is classified as a cosmetic ingredient in our database. CAS number: Not assigned.

What is the Margin of Safety for Human Neonatal Fibroblast/Keratinocyte Conditioned Media?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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