Humulus Lupulus Flower Extract

INCI: HUMULUS LUPULUS FLOWER EXTRACT

CAS Number
8060-28-4 / 8016-25-9
Function
Antimicrobial, antidandruff, astringent, hair conditioning, skin conditioning, soothing
Safety Rating
GOOD

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes CIR reviewed (2024 published) โ€” safe in present practices of use and concentration when formulated to be non-sensitizing

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
moderate
Sensitization
moderate

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

CIR identified three constituents of concern: 8-prenylnaringenin (potent phytoestrogen), ฮฒ-myrcene (dermal irritant), and quercetin (genotoxicity potential). Formulators must employ GMP to limit these constituents and monitor for additive effects when combining with other botanicals containing similar compounds.

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Concern Level: Moderate

Regulatory Flags

plant-extract natural-origin

Frequently Asked Questions

Is Humulus Lupulus Flower Extract safe in cosmetics?

CIR identified three constituents of concern: 8-prenylnaringenin (potent phytoestrogen), ฮฒ-myrcene (dermal irritant), and quercetin (genotoxicity potential). Formulators must employ GMP to limit these constituents and monitor for additive effects when combining with other botanicals containing similar compounds. The EU classifies Humulus Lupulus Flower Extract as "permitted". Safety rating: GOOD.

Is Humulus Lupulus Flower Extract allowed in the EU?

Humulus Lupulus Flower Extract EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Humulus Lupulus Flower Extract do in cosmetics?

Humulus Lupulus Flower Extract functions as: Antimicrobial, antidandruff, astringent, hair conditioning, skin conditioning, soothing. It is classified as a cosmetic ingredient in our database. CAS number: 8060-28-4 / 8016-25-9.

What is the Margin of Safety for Humulus Lupulus Flower Extract?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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