Moderate Cosmetic Ingredient NOAEL Data GHS Classified

Hydrobromic Acid

INCI: HYDROBROMIC ACID

CAS Number
10035-10-6
Function
Buffering / pH adjuster
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status prohibited
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Permitted โ€” no specific cosmetic prohibition under 21 CFR; used as pH adjuster

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
negligible
Sensitization
none

Calculate MoS for your specific formulation with the MoS Calculator.

Toxicological Studies

1 study endpoint found for Hydrobromic Acid. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.

Endpoint Value Route Species Study Type Source
LOAEL 10 ppm 1994 code:3544 inhalation REACH

GHS Hazard Classification

Globally Harmonized System classification per ECHA C&L inventory and ILO/WHO International Chemical Safety Cards.

Short-term Exposure Effects
The substance is corrosive to the eyes, skin and respiratory tract. Inhalation of this gas may cause lung oedema. See Notes. Rapid evaporation of the liquid may cause frostbite.
Routes of Exposure
The substance can be absorbed into the body by inhalation.

Expert Verdict

Highly corrosive in concentrated form. Must be used only at dilutions sufficient to achieve target pH (typically pH 3โ€“8 in finished product). Final product pH must be documented in CPSR. Bromide ion residual should be considered.

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Concern Level: Moderate

Frequently Asked Questions

Is Hydrobromic Acid safe in cosmetics?

Highly corrosive in concentrated form. Must be used only at dilutions sufficient to achieve target pH (typically pH 3โ€“8 in finished product). Final product pH must be documented in CPSR. Bromide ion residual should be considered. The EU classifies Hydrobromic Acid as "prohibited". Safety rating: MODERATE. 1 toxicological study endpoint(s) are available in our database.

Is Hydrobromic Acid allowed in the EU?

Hydrobromic Acid EU regulatory status: prohibited. This is based on EU Regulation 1223/2009 and its amendments.

What does Hydrobromic Acid do in cosmetics?

Hydrobromic Acid functions as: Buffering / pH adjuster. It is classified as a cosmetic ingredient in our database. CAS number: 10035-10-6.

What is the Margin of Safety for Hydrobromic Acid?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

What is the NOAEL for Hydrobromic Acid?

The NOAEL (No Observed Adverse Effect Level) for Hydrobromic Acid is 10 ppm based on a inhalation study via 1994 route in code:3544. Source: REACH.

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