Excellent Cosmetic Ingredient NOAEL Data

Hydrogenated Castor Oil

INCI: HYDROGENATED CASTOR OIL

CAS Number
8001-78-3
Function
Viscosity controlling, skin conditioning, emulsion stabiliser
Safety Rating
EXCELLENT

Regulatory Status

🇪🇺 EU Status permitted
🇺🇸 US Status permitted
US Notes Permitted — CIR safe as used (IJT 26(S3):31–77, 2007); also cleared for food-contact surfaces per 21 CFR 178.3280

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
low
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Toxicological Studies

10 study endpoints found for Hydrogenated Castor Oil. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.

Endpoint Value Route Species Study Type Source
NOAEL 1000 mg/kg bw/day oral rat oral REACH
NOAEL 10 other oral rat oral REACH
NOAEL >=1333 mg/kg bw/day oral rat oral REACH
NOAEL 1000 mg/kg bw/day oral rat oral REACH
NOAEL 15 other oral dog oral REACH
NOAEL 200000 mg/kg bw/day oral rat oral REACH
NOAEL 3500 mg/kg bw/day oral rat oral REACH
NOAEL >=15 other oral rat oral REACH
NOAEL 1000 mg/kg bw/day oral rat oral REACH
NOAEL >=1333 mg/kg bw/day oral rat oral REACH

Expert Verdict

Trace castor bean allergens may persist at low concentrations; 3 published case reports of contact dermatitis in pre-sensitised subjects.

⚠️
Concern Level: Low

Regulatory Flags

plant-oil potential-allergen eu_children_restricted epa_safer_alternative ifra_fragrance

Frequently Asked Questions

Is Hydrogenated Castor Oil safe in cosmetics?

Trace castor bean allergens may persist at low concentrations; 3 published case reports of contact dermatitis in pre-sensitised subjects. The EU classifies Hydrogenated Castor Oil as "permitted". Safety rating: EXCELLENT. 10 toxicological study endpoint(s) are available in our database.

Is Hydrogenated Castor Oil allowed in the EU?

Hydrogenated Castor Oil EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Hydrogenated Castor Oil do in cosmetics?

Hydrogenated Castor Oil functions as: Viscosity controlling, skin conditioning, emulsion stabiliser. It is classified as a cosmetic ingredient in our database. CAS number: 8001-78-3.

What is the Margin of Safety for Hydrogenated Castor Oil?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

What is the NOAEL for Hydrogenated Castor Oil?

The NOAEL (No Observed Adverse Effect Level) for Hydrogenated Castor Oil is 1000 mg/kg bw/day based on a oral study via oral route in rat. A total of 10 study endpoints are available. Source: REACH.

Compliance Tools

Check Hydrogenated Castor Oil compliance across multiple jurisdictions:

🔬
Ingredient Decoder
Paste a full ingredient list for instant analysis
 🌸
82 Allergen Checker
Check for EU declarable fragrance allergens
 🧪
Substance Compliance
Check compliance across 55 jurisdictions
 🧮
MoS Calculator
Calculate Margin of Safety using SCCS methodology
 ⚗️
Heavy Metal Limits
Compare limits across jurisdictions

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