Hydrolyzed Actin

INCI: HYDROLYZED ACTIN

CAS Number
222400-31-9
Function
Hair conditioning, skin conditioning
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Permitted, not restricted under 21 CFR. CIR searched this ingredient in tissue-derived proteins assessment with only 8 literature hits, 0 useful.

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
moderate
Sensitization
moderate

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Animal-derived protein from muscle tissue requiring BSE/TSE risk assessment per EU Regulation 1223/2009 Article 15; source species and hydrolysate molecular weight distribution must be documented; limited published safety literature available.

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Concern Level: Moderate

Frequently Asked Questions

Is Hydrolyzed Actin safe in cosmetics?

Animal-derived protein from muscle tissue requiring BSE/TSE risk assessment per EU Regulation 1223/2009 Article 15; source species and hydrolysate molecular weight distribution must be documented; limited published safety literature available. The EU classifies Hydrolyzed Actin as "permitted". Safety rating: MODERATE.

Is Hydrolyzed Actin allowed in the EU?

Hydrolyzed Actin EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Hydrolyzed Actin do in cosmetics?

Hydrolyzed Actin functions as: Hair conditioning, skin conditioning. It is classified as a cosmetic ingredient in our database. CAS number: 222400-31-9.

What is the Margin of Safety for Hydrolyzed Actin?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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