Hydroxymethoxybenzyl Pelargonamide
INCI: HYDROXYMETHOXYBENZYL PELARGONAMIDE
Regulatory Status
For full compliance data across 55 jurisdictions, use the Substance Compliance tool.
Safety Data
Calculate MoS for your specific formulation with the MoS Calculator.
Toxicological Studies
2 study endpoints found for Hydroxymethoxybenzyl Pelargonamide. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.
| Endpoint | Value | Route | Species | Study Type | Source |
|---|---|---|---|---|---|
| NOAEL | 8.63 mg/kg bw/day | oral | rat | Subchronic | COSMOS_DB |
| dose_tested | 8.63 mg/kg bw/day | oral | rat | Subchronic | COSMOS_DB |
Expert Verdict
Synthetic capsaicin analog and TRPV1 agonist causing dose-dependent burning and warming sensation; strict concentration control required; mucous membrane contact contraindicated; highest reported use in rinse-off products at 0.00005%; IFRA restrictions may apply.
Regulatory Flags
Frequently Asked Questions
Is Hydroxymethoxybenzyl Pelargonamide safe in cosmetics?
Synthetic capsaicin analog and TRPV1 agonist causing dose-dependent burning and warming sensation; strict concentration control required; mucous membrane contact contraindicated; highest reported use in rinse-off products at 0.00005%; IFRA restrictions may apply. The EU classifies Hydroxymethoxybenzyl Pelargonamide as "permitted". Safety rating: MODERATE. 2 toxicological study endpoint(s) are available in our database.
Is Hydroxymethoxybenzyl Pelargonamide allowed in the EU?
Hydroxymethoxybenzyl Pelargonamide EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Hydroxymethoxybenzyl Pelargonamide do in cosmetics?
Hydroxymethoxybenzyl Pelargonamide functions as: Hair conditioning, warming agent, fragrance ingredient. It is classified as a cosmetic ingredient in our database. CAS number: 2444-46-4.
What is the Margin of Safety for Hydroxymethoxybenzyl Pelargonamide?
not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
What is the NOAEL for Hydroxymethoxybenzyl Pelargonamide?
The NOAEL (No Observed Adverse Effect Level) for Hydroxymethoxybenzyl Pelargonamide is 8.63 mg/kg bw/day based on a Subchronic study via oral route in rat. A total of 2 study endpoints are available. Source: COSMOS_DB.
Compliance Tools
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Related Ingredients
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