Hydroxypropylcellulose

INCI: HYDROXYPROPYLCELLULOSE

CAS Number
9004-64-2 [^1_3]
Function
Binding, emulsifying, emulsion stabilising, film forming, viscosity increasing
Safety Rating
EXCELLENT

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Permitted; FDA GRAS for food use (21 CFR 172.870); CIR safe as cosmetic ingredient

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
negligible
Sensitization
none

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Essentially nontoxic by all routes tested. Nonirritating to slightly irritating to skin at concentrations up to 100%. No mutagenic activity demonstrated. No reproductive or developmental effects.

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Concern Level: None

Frequently Asked Questions

Is Hydroxypropylcellulose safe in cosmetics?

Essentially nontoxic by all routes tested. Nonirritating to slightly irritating to skin at concentrations up to 100%. No mutagenic activity demonstrated. No reproductive or developmental effects. The EU classifies Hydroxypropylcellulose as "permitted". Safety rating: EXCELLENT.

Is Hydroxypropylcellulose allowed in the EU?

Hydroxypropylcellulose EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Hydroxypropylcellulose do in cosmetics?

Hydroxypropylcellulose functions as: Binding, emulsifying, emulsion stabilising, film forming, viscosity increasing. It is classified as a cosmetic ingredient in our database. CAS number: 9004-64-2 [^1_3].

What is the Margin of Safety for Hydroxypropylcellulose?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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