Ilex Rotunda Extract

INCI: ILEX ROTUNDA EXTRACT

CAS Number
Not confirmed — verify with supplier CoA
Function
Skin conditioning
Safety Rating
MODERATE

Regulatory Status

🇪🇺 EU Status permitted
🇺🇸 US Status permitted
US Notes Permitted — not listed as prohibited/restricted under 21 CFR 700

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
moderate
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Active compounds include pedunculoside and syringin; used in TCM as bark extract for cardiovascular indications with potency at high concentrations requiring evaluation; dose-response data needed to support claimed anti-wrinkle efficacy range.

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Concern Level: Moderate

Regulatory Flags

plant-extract

Frequently Asked Questions

Is Ilex Rotunda Extract safe in cosmetics?

Active compounds include pedunculoside and syringin; used in TCM as bark extract for cardiovascular indications with potency at high concentrations requiring evaluation; dose-response data needed to support claimed anti-wrinkle efficacy range. The EU classifies Ilex Rotunda Extract as "permitted". Safety rating: MODERATE.

Is Ilex Rotunda Extract allowed in the EU?

Ilex Rotunda Extract EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Ilex Rotunda Extract do in cosmetics?

Ilex Rotunda Extract functions as: Skin conditioning. It is classified as a cosmetic ingredient in our database. CAS number: Not confirmed — verify with supplier CoA.

What is the Margin of Safety for Ilex Rotunda Extract?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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